College of Public Health, Temple University, Philadelphia, PA, USA.
School of Social Work, Temple University, Philadelphia, PA, USA.
Obes Rev. 2021 Jul;22(7):e13204. doi: 10.1111/obr.13204. Epub 2021 Jan 27.
Adverse childhood experiences (ACEs) are associated with numerous physical and mental health issues in children and adults. The effect of ACEs on development of childhood obesity is less understood. This systematic review was undertaken to synthesize the quantitative research examining the relationship between ACEs and childhood obesity. PubMed, PsycInfo, and Web of Science were searched in July 2020; Rayyan was used to screen studies, and the Newcastle-Ottawa Scale was used to assess risk of bias. The search resulted in 6,966 studies screened at title/abstract and 168 at full-text level. Twenty-four studies met inclusion criteria. Study quality was moderate, with greatest risk of bias due to method of assessment of ACEs or sample attrition. Findings suggest ACEs are associated with childhood obesity. Girls may be more sensitive to obesity-related effects of ACEs than boys, sexual abuse appears to have a greater effect on childhood obesity than other ACEs, and co-occurrence of multiple ACEs may be associated with greater childhood obesity risk. Further, the effect of ACEs on development of childhood obesity may take 2-5 years to manifest. Considered collectively, findings suggest a need for greater attention to ACEs in the prevention and treatment of childhood obesity.
不良的儿童期经历（ACEs）与儿童和成人的许多身心健康问题有关。ACEs 对儿童肥胖症发展的影响了解较少。本系统评价旨在综合定量研究，探讨 ACEs 与儿童肥胖症之间的关系。2020 年 7 月在 PubMed、PsycInfo 和 Web of Science 上进行了检索；使用 Rayyan 筛选研究，使用纽卡斯尔-渥太华量表评估偏倚风险。检索结果在标题/摘要中筛选出 6966 项研究，在全文水平上筛选出 168 项研究。24 项研究符合纳入标准。研究质量为中等，最大的偏倚风险是由于 ACEs 的评估方法或样本流失。研究结果表明 ACEs 与儿童肥胖症有关。与男孩相比，女孩可能对 ACE 相关的肥胖影响更为敏感，性虐待对儿童肥胖的影响似乎大于其他 ACEs，多种 ACEs 的同时发生可能与更大的儿童肥胖风险有关。此外，ACEs 对儿童肥胖症发展的影响可能需要 2-5 年才能显现。综合来看，这些发现表明需要更加关注 ACEs 在儿童肥胖症的预防和治疗中的作用。
