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新型冠状病毒 2019 型心脏病表现:初步报告。

Cardiac manifestation of corona virus disease 2019: a preliminary report.

机构信息

Department of Medicine, General Hospital Ifako-Ijaiye, Lagos, Nigeria. Email:

Department of Medicine, General Hospital Ifako-Ijaiye, Lagos, Nigeria.

出版信息

Cardiovasc J Afr. 2021;32(6):297-300. doi: 10.5830/CVJA-2020-061. Epub 2021 Jan 14.

Abstract

BACKGROUND

Corona virus disease 2019 (COVID-19) is a multi-systemic illness that can present with cardiac complications. This report describes the preliminary findings of cardiac manifestations seen in patients managed in three centres in Lagos, Nigeria.

METHODS

Ten patients, part of an ongoing study of patients admitted in three centres in Lagos, Nigeria, with COVID-19 diagnosed with reverse transcriptase polymerase chain reaction (RT-PCR) or serology were retrospectively studied for cardiac manifestations.

RESULTS

The mean (SD) age was 52.5 ± 18.79 years (with a minimum of 17 years and maximum of 79 years). Six patients were female and four were male. Hypertension was seen in 70%, diabetes in 50% and obesity in 60% of patients. All had elevated inflammatory markers. Only four patients had bilateral pneumonia. The rest had only cardiac manifestations. Six patients presented with de novo heart failure and one had decompensated heart failure. A set of three patients had individually fulminant myocarditis, probable pulmonary embolism and stress cardiomyopathy, respectively.

CONCLUSIONS

This study shows that co-morbidities are common in patients with COVID-19 and cardiac complications. The array of cardiac complications is large, with the commonest being heart failure.

摘要

背景

2019 年冠状病毒病(COVID-19)是一种多系统疾病,可引起心脏并发症。本报告描述了在尼日利亚拉各斯的三个中心治疗的患者中观察到的心脏表现的初步发现。

方法

10 名患者是正在进行的尼日利亚拉各斯三个中心 COVID-19 住院患者研究的一部分,通过逆转录聚合酶链反应(RT-PCR)或血清学诊断为 COVID-19,对其心脏表现进行了回顾性研究。

结果

平均(SD)年龄为 52.5 ± 18.79 岁(最小 17 岁,最大 79 岁)。6 名患者为女性,4 名患者为男性。70%的患者患有高血压,50%的患者患有糖尿病,60%的患者患有肥胖症。所有患者的炎症标志物均升高。仅 4 例患者患有双侧肺炎。其余患者仅表现为心脏症状。6 例患者新发心力衰竭,1 例患者失代偿性心力衰竭。一组 3 例患者分别患有暴发性心肌炎、可能的肺栓塞和应激性心肌病。

结论

本研究表明,COVID-19 患者合并症常见,且伴有心脏并发症。心脏并发症种类繁多,最常见的是心力衰竭。

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