Sozio Stephen J, Jhawar Sachin, Wang Yaqun, Sayan Mutlay, Parikh Rahul, Kim Sung
Rutgers Cancer Institute of New Jersey, Department of Radiation Oncology, New Brunswick, NJ, USA.
The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Asian Pac J Cancer Prev. 2021 Jan 1;22(1):195-199. doi: 10.31557/APJCP.2021.22.1.195.
Recreational use of the betel nut, which is common among the South Asian population, is a known risk factor for developing Head and Neck cancer. As South Asians comprise a significant proportion of the United States population, we seek to determine if those living within the country experience a higher rate of head and neck cancers compared to other races.
Data of patients diagnosed with head & neck cancers from 2010-2016 was collected from the National Cancer Database® and compared to race-matched US census data for each corresponding year to calculate incidence. Pairwise comparisons were performed between the incidence for South Asians versus Whites and South Asians versus Blacks using one sided Chi-square tests.
South Asians experienced a significantly higher incidence of buccal mucosa/vestibule cancers when compared to Whites or Blacks for every year between 2010-2016, but a comparatively lower incidence of larynx or oropharynx cancers.
South Asians residing within the United States have a higher incidence of buccal mucosa/vestibule cancers, but a lower incidence of more common cancers, such as larynx or oropharynx cancer. This may suggest that the etiology behind the high buccal mucosa/vestibule cancer incidence is due to a social habit, as opposed to an inherent racial susceptibility.
嚼食槟榔在南亚人群中很常见，是已知的头颈癌发病风险因素。由于南亚人在美国人口中占相当大的比例，我们试图确定在美国境内生活的南亚人与其他种族相比，头颈癌发病率是否更高。
从国家癌症数据库收集2010 - 2016年被诊断为头颈癌患者的数据，并与每年种族匹配的美国人口普查数据进行比较以计算发病率。使用单侧卡方检验对南亚人与白人以及南亚人与黑人的发病率进行两两比较。
在2010 - 2016年期间，每年南亚人颊黏膜/前庭癌的发病率显著高于白人和黑人，但喉癌或口咽癌的发病率相对较低。
居住在美国的南亚人颊黏膜/前庭癌发病率较高，但喉癌或口咽癌等更常见癌症的发病率较低。这可能表明颊黏膜/前庭癌高发病率背后的病因是一种社会习惯，而非内在的种族易感性。
