头颈部癌症发病率和趋势的种族/民族和性别差异。
Disparities in head and neck cancer incidence and trends by race/ethnicity and sex.
机构信息
Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
出版信息
Head Neck. 2023 Jan;45(1):75-84. doi: 10.1002/hed.27209. Epub 2022 Oct 6.
BACKGROUND
The epidemiology of head and neck cancer (HNC) sites differ substantially. This study compares HNC incidence trends by site and demographic subgroups.
METHODS
We used the U.S. Cancer Statistics Public Use Database to calculate HNC incidence rates per 100 000. We assessed trends with annual percent change (APC) longitudinally from 2001 to 2017.
RESULTS
The oropharyngeal cancer incidence APC decreased from 4.38% (95% CI: 3.6, 5.1) to 2.93% (2.5, 3.3) in 2008 among White males. Oral cavity cancer incidence rose in Other race males (APC 2.5% [1.6, 3.36]) and White females (APC: 0.96% [0.7, 1.2]). Although decreasing (APC: -1.15% [-1.48, -0.83]), laryngeal cancer incidence remained disproportionately high among Black males.
CONCLUSIONS
Notable incidence trends occurred in non-White groups at non-oropharyngeal sites. With parity of smoking rates by race, differing sexual behaviors, and shifting demographics by race and sex, future studies of HNC trends should consider stratifying analyses to understand health disparities.
背景
头颈部癌症（HNC）的发病部位存在显著差异。本研究比较了不同部位和人口统计学亚组的 HNC 发病趋势。
方法
我们使用美国癌症统计公共数据库计算每 100000 人 HNC 的发病率。我们评估了 2001 年至 2017 年期间的年度百分比变化（APC）的纵向趋势。
结果
2008 年，白人男性的口咽癌发病率 APC 从 4.38%（95%CI：3.6，5.1）降至 2.93%（2.5，3.3）。其他种族男性的口腔癌发病率上升（APC 2.5%[1.6，3.36]）和白人女性（APC：0.96%[0.7，1.2]）。尽管喉癌发病率呈下降趋势（APC：-1.15%[-1.48，-0.83]），但在黑人男性中仍居高不下。
结论
在非口咽部位的非白人组中，发病率趋势明显。随着种族间吸烟率的均等化、不同的性行为以及种族和性别的人口结构的变化，未来对头颈部癌症趋势的研究应考虑分层分析，以了解健康差距。
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