基因组修复在 ACS TOXI 会议上成为焦点。
Genome Repair Takes a Spotlight during the ACS TOXI Meeting.
机构信息
Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Department of Chemistry and Biochemistry, Baylor University, Waco, Texas 76798, United States.
出版信息
Chem Res Toxicol. 2021 Mar 15;34(3):675-677. doi: 10.1021/acs.chemrestox.0c00438. Epub 2021 Jan 28.
Abstract
DNA damage and mutations are a major primary cause of cancer. Chemical bombardment of DNA is a major contributor to DNA damage. The Division of Chemical Toxicology recently hosted a panel of researchers who provided updates on the field of chemical toxicology at the nexus of DNA damage and repair.
摘要
DNA 损伤和突变是癌症的主要原发性原因。化学物质对 DNA 的攻击是导致 DNA 损伤的主要原因。化学毒理学司最近举办了一个研究人员小组会议，介绍了在 DNA 损伤和修复的交汇点的化学毒理学领域的最新研究进展。
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Comparison of the Base Excision and Direct Reversal Repair Pathways for Correcting 1,-Ethenoadenine in Strongly Positioned Nucleosome Core Particles.比较碱基切除和直接反转修复途径纠正强定位核小体核心颗粒中 1,-乙烯腺嘌呤。
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