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组蛋白甲基化在表观遗传调控和温度响应中的作用。

Histone methylation in epigenetic regulation and temperature responses.

机构信息

State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, CAS Center for Excellence in Molecular Plant Sciences, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, CAS Center for Excellence in Molecular Plant Sciences, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

出版信息

Curr Opin Plant Biol. 2021 Jun;61:102001. doi: 10.1016/j.pbi.2021.102001. Epub 2021 Jan 25.

DOI:10.1016/j.pbi.2021.102001
PMID:33508540
Abstract

Methylation of histones on different lysine residues is dynamically added by distinct writer enzymes, interpreted by reader proteins, and removed by eraser enzymes. This epigenetic mark has widespread, dynamic roles in plant development and environmental responses. For example, histone methylation plays a key role in mediating plant responses to temperature, including alterations of flowering time. In this review, we summarize recent advances in understanding the mechanism by which histone methylation regulates these processes, and discuss the role of histone methylation in temperature responses, based on data from Arabidopsis thaliana.

摘要

组蛋白上不同赖氨酸残基的甲基化是由不同的写入酶动态添加的,由读取蛋白解释,并由擦除酶去除。这种表观遗传标记在植物发育和环境响应中具有广泛的、动态的作用。例如,组蛋白甲基化在介导植物对温度的反应中起着关键作用,包括开花时间的改变。在这篇综述中,我们总结了近年来对组蛋白甲基化调控这些过程的机制的理解进展,并基于拟南芥的数据讨论了组蛋白甲基化在温度响应中的作用。

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