Research Institute of Biotechnology and Medical Converged Science, Dongguk University-Seoul, Ilsandong-gu, Goyang-si, Gyeonggido 10326, Republic of Korea.
Department of Biological and Environmental Science, Dongguk University, Ilsandong-gu, Goyang-si, Gyonggido 10326, Republic of Korea.
Bioresour Technol. 2021 Apr;325:124685. doi: 10.1016/j.biortech.2021.124685. Epub 2021 Jan 9.
Polyhydroxyalkanoates (PHA) are appealing as an important alternative to replace synthetic plastics owing to its comparable physicochemical properties to that of synthetic plastics, and biodegradable and biocompatible nature. This review gives an inclusive overview of the current research activities dealing with PHA production by utilizing different waste fluxes generated from food, milk and sugar processing industries. Valorization of these waste fluxes makes the process cost effective and practically applicable. Recent advances in the approaches adopted for waste treatment, fermentation strategies, and genetic engineering can give insights to the researchers for future direction of waste to bioplastics production. Lastly, synthesis and application of PHA-nanocomposites, research and development challenges, future perspectives for sustainable and cost-effective PHB production are also discussed. In addition, the review addresses the useful information about the opportunities and confines associated with the sustainable PHA production using different waste streams and their evaluation for commercial implementation within a biorefinery.
聚羟基脂肪酸酯（PHA）是一种有吸引力的替代品，可以替代合成塑料，因为它具有与合成塑料相当的物理化学性质，并且具有可生物降解和生物相容性。本综述全面概述了利用食品、牛奶和糖加工行业产生的不同废物流生产 PHA 的当前研究活动。这些废物流的增值利用使该过程具有成本效益和实际应用价值。最近在废物处理方法、发酵策略和遗传工程方面的进展可以为研究人员提供未来从废物到生物塑料生产的方向的见解。最后，还讨论了 PHA-纳米复合材料的合成和应用、研究和开发挑战、可持续和具有成本效益的 PHB 生产的未来展望。此外，该综述还介绍了利用不同废物流生产可持续 PHA 的机会和限制的相关信息，以及它们在生物炼制厂中的商业实施的评估。
