School of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China.
School of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China; State Key Laboratory of Bio-fibers and Eco-textiles, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Institute of Marine Biobased Materials, Qingdao University, Qingdao 266071, China.
Spectrochim Acta A Mol Biomol Spectrosc. 2021 Apr 15;251:119468. doi: 10.1016/j.saa.2021.119468. Epub 2021 Jan 16.
N-doped carbon dots (N-CDs) were successfully synthesized via simple one-step hydrothermal carbonization using chitosan as carbon and nitrogen sources. The obtained N-CDs contained a variety of functional groups on the NCDs surface, and exhibited excitation-independent behavior and strong blue fluorescence with a relatively higher fluorescence quantum yield (QY = 35%). It also presented excellent water solubility, resistance to pH change, high ion strength and UV irradiation. Since the fluorescence of the N-CDs could be selectively quenched by NO, they could act as a fluorescent sensor for the determination of NO in real tap water and lake water samples with a wide linear range (1-500 μM) and low detection limit (0.1 μM). They could also be used for bacterial imaging as multicolor fluorescent probes. The results indicated that N-CDs could be a promising candidate material for biomedical applications.
氮掺杂碳点（N-CDs）是通过简单的一步水热碳化法，以壳聚糖作为碳源和氮源成功合成的。所得到的 N-CDs 在 NCDs 表面含有多种官能团，表现出与激发无关的行为和强的蓝色荧光，具有相对较高的荧光量子产率（QY=35%）。它还具有出色的水溶性、耐 pH 值变化、高离子强度和耐紫外光照射能力。由于 N-CDs 的荧光可以被 NO 选择性猝灭，因此它们可以作为荧光传感器用于测定实际自来水中和湖水样品中的 NO，具有较宽的线性范围（1-500 μM）和较低的检测限（0.1 μM）。它们还可以用作多色荧光探针进行细菌成像。结果表明，N-CDs 可能是一种有前途的用于生物医学应用的候选材料。
