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采用 Pipeline Flex with Shield 技术成功治疗破裂感染性大脑中动脉动脉瘤的血流导向治疗。

Successful flow diversion treatment of ruptured infectious middle cerebral artery aneurysms with the use of Pipeline Flex with Shield technology.

机构信息

Department of Neurosurgery, University of Texas Health San Antonio, San Antonio, TX, USA.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, USA.

出版信息

Interv Neuroradiol. 2021 Apr;27(2):225-229. doi: 10.1177/1591019921990506. Epub 2021 Jan 28.

Abstract

BACKGROUND

Rupture of infectious intracranial aneurysms (IIAs) is associated with a high likelihood of mortality. Endovascular treatment of IIAs via parent artery sacrifice offers good efficacy and outcomes; however, depending on the lesion's location, neurologic deficit may result.

CASE DESCRIPTION

We describe a pediatric patient with ruptured IIAs off the left middle cerebral artery (MCA) treated with coil embolization and endovascular flow diversion using the Pipeline Flex Embolization Device (PED) with Shield technology. We chose to place a flow diverter because 1) there was a second, more distal IIA not amenable to direct coil embolization, 2) there was significant potential for aneurysm regrowth and need for retreatment, and 3) we believed the diseased parent MCA needed to be reconstructed.

CONCLUSIONS

In the setting of previous hemicraniectomy, PED-Shield gave us the option to discontinue dual antiplatelet therapy should the patient require further neurosurgical intervention. Our case supports a role for PED-Shield to address ruptured pseudoaneurysms.

摘要

背景

感染性颅内动脉瘤(IIAs)破裂与高死亡率相关。通过牺牲载瘤动脉的血管内治疗 IIAs 可获得良好的疗效和结果;然而,根据病变的位置,可能会导致神经功能缺损。

病例描述

我们描述了一例左侧大脑中动脉(MCA)的破裂 IIAs 患儿,采用线圈栓塞和 Pipeline Flex 栓塞装置(PED)联合 Shield 技术进行血管内血流转向治疗。我们选择放置血流转向装置是因为 1)存在第二个更远端的 IIA,无法直接进行线圈栓塞,2)动脉瘤有较大的再生长和需要再次治疗的可能性,以及 3)我们认为病变的 MCA 需要重建。

结论

在先前行半脑切除术的情况下,如果患者需要进一步的神经外科干预,PED-Shield 为我们提供了停止双联抗血小板治疗的选择。我们的病例支持 PED-Shield 在治疗破裂假性动脉瘤中的作用。

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J Stroke Cerebrovasc Dis. 2019 Jul;28(7):e81-e82. doi: 10.1016/j.jstrokecerebrovasdis.2019.04.026. Epub 2019 May 14.
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Paediatric aneurysms - Review of endovascular treatment strategies.小儿动脉瘤 - 血管内治疗策略的综述。
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