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潜在的 COVID-19 治疗药物和疫苗:基于证据的综述。

Potential COVID-19 Therapeutic Agents and Vaccines: An Evidence-Based Review.

机构信息

Department of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

J Clin Pharmacol. 2021 Apr;61(4):429-460. doi: 10.1002/jcph.1822. Epub 2021 Mar 5.

DOI:10.1002/jcph.1822
PMID:33511638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8014753/
Abstract

Since the early days of 2020, the severe acute respiratory syndrome coronavirus 2 pandemic has become a global health concern. Currently, some therapies and vaccines have received US Food and Drug Administration approval or emergency use authorization for the management of coronavirus disease 2019. According to the pathophysiology of the disease, several medications have been evaluated in different clinical conditions of the disease. Evidence-based reviewing and categorizing these medications can guide the clinicians to select the proper medications according to each patient's condition. Therefore, we performed this review to categorize the coronavirus disease 2019 potential therapeutics and vaccines.

摘要

自 2020 年初以来,严重急性呼吸综合征冠状病毒 2 大流行已成为全球关注的健康问题。目前,一些疗法和疫苗已获得美国食品和药物管理局批准或紧急使用授权,用于治疗 2019 年冠状病毒病。根据疾病的病理生理学,几种药物已在疾病的不同临床情况下进行了评估。对这些药物进行循证审查和分类可以指导临床医生根据每个患者的病情选择合适的药物。因此,我们进行了这项审查,以对 2019 年冠状病毒病的潜在治疗方法和疫苗进行分类。

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