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子痫前期:中低收入国家应该普遍筛查还是普遍预防?

Pre-eclampsia: Universal Screening or Universal Prevention for Low and Middle-Income Settings?

机构信息

Department of Gynecology and Obstetrics, Botucatu Medical School, Universidade Estadual Paulista "Júlio de Mesquita Filho," Botucatu, SP, Brazil.

Department of Obstetrics and Gynecology, Faculty of Medicine, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.

出版信息

Rev Bras Ginecol Obstet. 2021 Jan;43(1):61-65. doi: 10.1055/s-0040-1713803. Epub 2021 Jan 29.

Abstract

Pre-eclampsia (PE) is a severe disorder that affects up to 8% of all pregnancies and represents an important cause of maternal and perinatal morbidity and mortality. The screening of the disease is a subject of studies, but the complexity and uncertainties regarding its etiology make this objective a difficult task. In addition, the costs related to screening protocols, the heterogeneity of the most affected populations and the lack of highly effective prevention methods reduce the potential of current available algorithms for screening. Thus, the National Specialized Commission of Hypertension in Pregnancy of the Brazilian Association of Gynecology and Obstetrics Federation (Febrasgo, in the Portuguese acronym) (NSC Hypertension in Pregnancy of the Febrasgo) considers that there are no screening algorithms to be implemented in the country to date and advocates that Aspirin and calcium should be widely used.

摘要

子痫前期 (PE) 是一种严重的疾病,影响多达 8%的所有妊娠,并代表了产妇和围产儿发病率和死亡率的一个重要原因。该疾病的筛查是研究的主题,但由于其病因的复杂性和不确定性,这一目标是一项艰巨的任务。此外,与筛查方案相关的成本、受影响人群的异质性以及缺乏高度有效的预防方法,降低了当前可用的筛查算法的潜力。因此,巴西妇产科联合会高血压专业国家委员会 (NSC Hypertension in Pregnancy of the Febrasgo) 认为,目前该国还没有可实施的筛查算法,并主张广泛使用阿司匹林和钙。

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1
Pre-eclampsia/Eclampsia.
Rev Bras Ginecol Obstet. 2019 May;41(5):e1-e2. doi: 10.1055/s-0040-1702167. Epub 2020 Feb 17.
3
Antiplatelet agents for preventing pre-eclampsia and its complications.用于预防子痫前期及其并发症的抗血小板药物。
Cochrane Database Syst Rev. 2019 Oct 30;2019(10):CD004659. doi: 10.1002/14651858.CD004659.pub3.
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Prediction of pre-eclampsia: review of reviews.子痫前期预测:综述研究。
Ultrasound Obstet Gynecol. 2019 Jul;54(1):16-27. doi: 10.1002/uog.20117.

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