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不同引导骨再生程序对伤口闭合后骨移植轮廓的影响:一项回顾性队列研究

The Influence of Different Guided Bone Regeneration Procedures on the Contour of Bone Graft after Wound Closure: A Retrospective Cohort Study.

作者信息

Wang Maoxia, Zhang Xiaoqing, Li Yazhen, Mo Anchun

机构信息

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

出版信息

Materials (Basel). 2021 Jan 27;14(3):583. doi: 10.3390/ma14030583.

Abstract

The aim of this study was to evaluate the impact of different guided bone regeneration (GBR) procedures on bone graft contour after wound closure in lateral ridge augmentation. A total of 48 patients with 63 augmented sites were included in this study. Participants were divided into 4 groups ( = 12 in each group) based on different surgical procedures: group 1: particulate bone substitute + collagen membrane; group 2: particulate bone substitute + collagen membrane + healing cap, group 3: particulate bone substitute + injectable platelet-rich fibrin (i-PRF) + collagen membrane; group 4: particulate bone substitute + i-PRF + surgical template + collagen membrane. After wound closure, the thickness of labial graft was measured at 0-5 mm apical to the implant shoulder (T0-T5). At T0-T2, the thickness of labial graft in group 4 was significantly higher than the other three groups ( < 0.05). And group 4 showed significantly more labial graft thickness than group 1 and group 2 at T3-T5 ( < 0.05). Within the limitations of this study, the use of i-PRF in combination with the surgical template in GBR may contribute to achieving an appropriate bone graft contour after wound closure.

摘要

本研究的目的是评估不同引导骨再生(GBR)程序对侧方牙槽嵴增高术后伤口闭合时骨移植轮廓的影响。本研究共纳入48例患者的63个增高部位。根据不同手术程序,参与者被分为4组(每组n = 12):第1组:颗粒状骨替代物+胶原膜;第2组:颗粒状骨替代物+胶原膜+愈合帽;第3组:颗粒状骨替代物+可注射富血小板纤维蛋白(i-PRF)+胶原膜;第4组:颗粒状骨替代物+i-PRF+手术模板+胶原膜。伤口闭合后,在种植体肩部根尖方向0-5mm处测量唇侧移植骨的厚度(T0-T5)。在T0-T2时,第4组唇侧移植骨的厚度显著高于其他三组(P < 0.05)。在T3-T5时,第4组唇侧移植骨厚度显著高于第1组和第2组(P < 0.05)。在本研究的局限性内,GBR中使用i-PRF联合手术模板可能有助于伤口闭合后获得合适的骨移植轮廓。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f96e/7865681/bef53958c07a/materials-14-00583-g001.jpg

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