光致变色卷曲螺旋中的构象控制。
Conformational control in a photoswitchable coiled coil.
机构信息
Department of Chemistry, New York University, 100 Washington Square East, New York, NY 10003, USA.
出版信息
Chem Commun (Camb). 2021 Feb 15;57(12):1442-1445. doi: 10.1039/d0cc08318f.
Abstract
The coiled coil is a common protein tertiary structure intimately involved in mediating protein recognition and function. Due to their structural simplicity, coiled coils have served as attractive scaffolds for the development of functional biomaterials. Herein we describe the design of conformationally-defined coiled coil photoswitches as potential environmentally-sensitive biomaterials.
摘要
螺旋线圈是一种常见的蛋白质三级结构，它在介导蛋白质识别和功能中起着重要作用。由于其结构简单，螺旋线圈已成为功能性生物材料开发的有吸引力的支架。本文描述了设计构象确定的螺旋线圈光开关作为潜在的环境敏感型生物材料。
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