Lee Kyung-Yul, Kim Jin Woo, Park Mina, Suh Sang Hyun, Ahn Sung Jun
Department of Neurology, Gangnam Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea.
Department of Radiology, Gangnam Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea.
J Neuroradiol. 2022 May;49(3):258-266. doi: 10.1016/j.neurad.2021.01.009. Epub 2021 Jan 28.
Fluid-attenuation inversion recovery (FLAIR) vascular hyperintensity (FVH) is a common presentation on brain magnetic resonance images of patients with acute ischemic stroke. This sign is known as a sluggish collateral flow. Although FVH represents the large ischemic penumbra and collateral circulation, the clinical significance of FVH has not been established. Varying protocols for FLAIR, treatment differences, and heterogeneity of endpoints across studies have complicated the interpretation of FVH in patients with acute stroke. In this review article, we describe the mechanism of FVH, as well as its association with functional outcome, perfusion-weighted images, and large artery stenosis. In addition, we review the technological variables that affect FVH and discuss the future perspectives.
液体衰减反转恢复（FLAIR）血管高信号（FVH）是急性缺血性脑卒中患者脑磁共振成像中的常见表现。该征象被称为侧支循环血流缓慢。尽管FVH代表大面积缺血半暗带和侧支循环，但FVH的临床意义尚未明确。不同的FLAIR方案、治疗差异以及各研究终点的异质性使得急性脑卒中患者FVH的解读变得复杂。在这篇综述文章中，我们描述了FVH的机制，以及它与功能结局、灌注加权成像和大动脉狭窄的关系。此外，我们回顾了影响FVH的技术变量并探讨了未来前景。
