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Flow-mediated vasodilation through mechanosensitive G protein-coupled receptors in endothelial cells.内皮细胞中机械敏感性 G 蛋白偶联受体介导的血流介导的血管舒张。
Trends Cardiovasc Med. 2022 Feb;32(2):61-70. doi: 10.1016/j.tcm.2020.12.010. Epub 2021 Jan 3.
2
Rescue Treatment With High-Dose Gaseous Nitric Oxide in Spontaneously Breathing Patients With Severe Coronavirus Disease 2019.严重2019冠状病毒病自主呼吸患者的高剂量气态一氧化氮抢救治疗
Crit Care Explor. 2020 Nov 16;2(11):e0277. doi: 10.1097/CCE.0000000000000277. eCollection 2020 Nov.
3
Implication of inhaled nitric oxide for the treatment of critically ill COVID-19 patients with pulmonary hypertension.吸入一氧化氮对治疗合并肺动脉高压的危重症 COVID-19 患者的意义。
ESC Heart Fail. 2021 Feb;8(1):714-718. doi: 10.1002/ehf2.13023. Epub 2020 Nov 17.
4
COVID-19 - A vascular disease.COVID-19 - 一种血管疾病。
Trends Cardiovasc Med. 2021 Jan;31(1):1-5. doi: 10.1016/j.tcm.2020.10.005. Epub 2020 Oct 14.
5
High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19).高浓度一氧化氮吸入疗法治疗重症 2019 冠状病毒病(COVID-19)孕妇。
Obstet Gynecol. 2020 Dec;136(6):1109-1113. doi: 10.1097/AOG.0000000000004128.
6
Endothelial cell infection and endotheliitis in COVID-19.新型冠状病毒肺炎中的内皮细胞感染与内皮炎
Lancet. 2020 May 2;395(10234):1417-1418. doi: 10.1016/S0140-6736(20)30937-5. Epub 2020 Apr 21.
7
Helix 8 is the essential structural motif of mechanosensitive GPCRs.螺旋 8 是机械敏感性 GPCR 的基本结构基序。
Nat Commun. 2019 Dec 19;10(1):5784. doi: 10.1038/s41467-019-13722-0.
8
Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.切应力诱导的内皮素肾上腺髓质素信号调节血管张力和血压。
J Clin Invest. 2019 Jun 17;129(7):2775-2791. doi: 10.1172/JCI123825.
9
GPR68 Senses Flow and Is Essential for Vascular Physiology.GPR68 感知流动,是血管生理学所必需的。
Cell. 2018 Apr 19;173(3):762-775.e16. doi: 10.1016/j.cell.2018.03.076.
10
Ion Channels in Endothelial Responses to Fluid Shear Stress.内皮细胞对流体切应力反应中的离子通道
Physiology (Bethesda). 2016 Sep;31(5):359-69. doi: 10.1152/physiol.00007.2016.

Editorial commentary: Could shear stress mimetics delay complications in COVID-19?

作者信息

Kim Boa, Arany Zolt

机构信息

Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.

Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.

出版信息

Trends Cardiovasc Med. 2022 Feb;32(2):71-72. doi: 10.1016/j.tcm.2021.01.004. Epub 2021 Jan 27.

DOI:10.1016/j.tcm.2021.01.004
PMID:33515686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7838584/
Abstract
摘要