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In response to: Multiple assays in a real-time RT-PCR severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak.

作者信息

Peñarrubia Luis, Ruiz Maria, Porco Roberto, Rao Sonia N, Vella Stephen A, Juanola-Falgarona Martí, Manissero Davide, López-Fontanals Marta, Pareja Josep

机构信息

STAT-Dx Life, S.L. (a QIAGEN Company), Barcelona, Spain.

QIAGEN, Inc., Germantown, MD, USA.

出版信息

Int J Infect Dis. 2021 Apr;105:241-242. doi: 10.1016/j.ijid.2021.01.049. Epub 2021 Jan 27.

DOI:10.1016/j.ijid.2021.01.049
PMID:33515772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7838576/
Abstract
摘要

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In response to: Multiple assays in a real-time RT-PCR severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak.回应：在2019冠状病毒病疫情期间，实时逆转录聚合酶链反应严重急性呼吸综合征冠状病毒2（SARS-CoV-2）检测板中的多种检测方法可降低新基因组变异导致敏感性丧失的风险。
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本文引用的文献

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S-Variant SARS-CoV-2 Lineage B1.1.7 Is Associated With Significantly Higher Viral Load in Samples Tested by TaqPath Polymerase Chain Reaction.S 变异株 SARS-CoV-2 谱系 B1.1.7 与 TaqPath 聚合酶链反应检测样本中的病毒载量显著升高相关。
J Infect Dis. 2021 May 28;223(10):1666-1670. doi: 10.1093/infdis/jiab082.
2
Fast-spreading U.K. virus variant raises alarms.传播迅速的英国病毒变种引发警报。
Science. 2021 Jan 1;371(6524):9-10. doi: 10.1126/science.371.6524.9.
3
No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2.没有证据表明 SARS-CoV-2 反复出现的突变会增加传染性。
Nat Commun. 2020 Nov 25;11(1):5986. doi: 10.1038/s41467-020-19818-2.
4
Multiple assays in a real-time RT-PCR SARS-CoV-2 panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak.实时 RT-PCR SARS-CoV-2 检测 panel 中的多重检测可以降低新型基因组变异导致的检测敏感性降低的风险，从而应对 COVID-19 大流行。
Int J Infect Dis. 2020 Aug;97:225-229. doi: 10.1016/j.ijid.2020.06.027. Epub 2020 Jun 12.