Department of Orthodontics, School of Life Dentistry at Tokyo, The Nippon Dental University, Tokyo, Japan.
Department of Orthodontics, School of Life Dentistry at Tokyo, The Nippon Dental University, Tokyo, Japan.
Arch Oral Biol. 2021 Apr;124:105038. doi: 10.1016/j.archoralbio.2021.105038. Epub 2021 Jan 13.
Wide individual variation observed in tooth agenesis patterns in patients with non-syndromic oligodontia could be affected by sexual dimorphism. Therefore, the present study investigated sex-associated differences in tooth agenesis patterns in patients with non-syndromic oligodontia.
Subjects were 108 male (ages 7-46 years) and 184 female (ages 7-43 years) orthodontic patients missing ≥6 permanent teeth, excluding third molars. The number of agenetic teeth per patient, excluding third molars, and the prevalence of agenesis of each tooth type were evaluated using panoramic radiographic images. Rankings of the most common tooth agenesis patterns in the maxillary and mandibular arches were calculated. The number of agenetic teeth per patient was compared between sexes using the Mann-Whitney test. The prevalence of tooth agenesis for each tooth type was compared between sexes using the χ and Fisher's exact tests with Bonferroni correction.
No significant sex difference in the distribution of the number of agenetic teeth was observed. The prevalence of agenesis of the maxillary second premolars was significantly higher in females (P < 0.007) and the prevalence of agenesis of the mandibular central incisors was significantly higher in males (P < 0.007). Sexual dimorphism was observed in the highly ranked tooth agenesis patterns.
No significant difference in the severity of tooth agenesis was observed between sexes; however, sexual dimorphism was observed in the tooth agenesis patterns of patients with non-syndromic oligodontia. Although various tooth agenesis patterns were identified, sex-specific tendencies suggest that categories can be utilized in future epidemiologic research and planning.
在非综合征性少牙症患者中，观察到牙齿缺失模式存在广泛的个体差异，这可能受到性二态性的影响。因此，本研究调查了非综合征性少牙症患者中与性别相关的牙齿缺失模式差异。
本研究共纳入 108 名男性（年龄 7-46 岁）和 184 名女性（年龄 7-43 岁）正畸患者，这些患者缺失≥6 颗恒牙（不包括第三磨牙）。使用全景放射影像评估每位患者缺失的非第三磨牙恒牙数量以及每种牙缺失类型的发生率。计算上颌和下颌弓中最常见的牙齿缺失模式的排名。使用 Mann-Whitney 检验比较男女患者的缺牙数量。使用 χ 和 Fisher 确切检验（Bonferroni 校正）比较男女患者中每种牙缺失类型的发生率。
未观察到缺牙数量的分布在性别之间存在显著差异。上颌第二前磨牙缺失的发生率在女性中显著更高（P<0.007），下颌中切牙缺失的发生率在男性中显著更高（P<0.007）。在高度排名的牙齿缺失模式中观察到性二态性。
未观察到性别间牙齿缺失严重程度存在显著差异；然而，在非综合征性少牙症患者的牙齿缺失模式中观察到了性二态性。尽管确定了各种牙齿缺失模式，但性别特异性趋势表明，在未来的流行病学研究和规划中可以利用这些类别。
