Lapalu Sophie, Izaaryene Ghizlane, Honoré Nadia, Couchoud Cécile
Service d'épidémiologie et de santé publique, registre REIN, CHU de Toulouse, faculté de médecine, 37, allées Jules-Guesdes, Toulouse, France.
Aix-Marseille université, EA 3279, santé publique, centre d'étude et de recherche sur les services de santé et la qualité de vie, Faculté de médecine, 27, boulevard Jean-Moulin, 13385 Marseille cedex 5, France; Cellule d'appui épidémiologique, registre REIN Provence-Alpes Côtes d'Azur et Corse, hôpital de La Conception, boulevard Baille, 13005 Marseille, France.
Nephrol Ther. 2021 Aug;17(4):218-225. doi: 10.1016/j.nephro.2020.11.005. Epub 2021 Jan 8.
The REIN registry is a national registry held by the French Biomedicine Agency. Its objective is the epidemiological monitoring of patients with end-stage chronic renal failure. This registry, backed by its expertise and its national network, has been able to very quickly set up epidemiological monitoring of chronic dialysis and/or transplant patients affected by SARS-CoV-2. The first results show a relatively low frequency of COVID-19 in dialysis patients (4.9%) contrary to what one might have feared. The frequency of SARS-CoV-2 infection in kidney transplant patients is 1.8% nationwide. All regions of France have not been affected in the same way. The prevalence of COVID-19 patients varied by region, reaching up to 10%. The probability of being affected was higher in men and diabetic patients. At October 19, among 3209 infected patients (dialysis and transplant), 573 died from a cause related to SARS-CoV-2. The case fatality in diagnosed cases was 18%. A weekly newsletter has been set up by the Biomedicine Agency using information transmitted by all of the epidemiological support units in the registry. The REIN registry was able to adapt to become a reactive health monitoring tool.
REIN登记处是法国生物医学机构设立的一个全国性登记处。其目标是对终末期慢性肾衰竭患者进行流行病学监测。该登记处凭借其专业知识和全国性网络，能够非常迅速地对受SARS-CoV-2感染的慢性透析和/或移植患者开展流行病学监测。初步结果显示，透析患者中COVID-19的感染频率相对较低（4.9%），这与人们可能担心的情况相反。全国范围内肾移植患者中SARS-CoV-2感染的频率为1.8%。法国所有地区受到的影响不尽相同。COVID-19患者的患病率因地区而异，最高可达10%。男性和糖尿病患者受感染的可能性更高。截至10月19日，在3209名受感染患者（透析和移植患者）中，有573人死于与SARS-CoV-2相关的原因。确诊病例的病死率为18%。生物医学机构利用登记处所有流行病学支持单位传递的信息，设立了一份每周时事通讯。REIN登记处能够进行调整，成为一个反应迅速的健康监测工具。
