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为何以及如何应在 2019 冠状病毒病大流行期间和之后提倡终末期肾病患者进行家庭透析?法国的观点。

Why and how should we promote home dialysis for patients with end-stage kidney disease during and after the coronavirus 2019 disease pandemic? A French perspective.

机构信息

Department of Nephrology and Dialysis, Hôpital Privé Claude Galien, Ramsay Santé, Quincy-sous-Sénart, France.

Collège de Médecine des Hôpitaux de Paris, Paris, France.

出版信息

J Nephrol. 2021 Aug;34(4):985-989. doi: 10.1007/s40620-021-01061-7. Epub 2021 Jun 1.

Abstract

The health crisis induced by the pandemic of coronavirus 2019 disease (COVID-19) has had a major impact on dialysis patients in France. The incidence of infection with acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first wave of the COVID-19 epidemic was 3.3% among dialysis patients-13 times higher than in the general population. The corresponding mortality rate was high, reaching 21%. As of 19th April, 2021, the cumulative prevalence of SARS-CoV-2 infection in French dialysis patients was 14%. Convergent scientific data from France, Italy, the United Kingdom and Canada show that home dialysis reduces the risk of SARS-CoV-2 infection by a factor of at least two. Unfortunately, home dialysis in France is not sufficiently developed: the proportion of dialysis patients being treated at home is only 7%. The obstacles to the provision of home care for patients with end-stage kidney disease in France include (i) an unfavourable pricing policy for home haemodialysis and nurse visits for assisted peritoneal dialysis (PD), (ii) insufficient training in home dialysis for nephrologists, (iii) the small number of administrative authorizations for home dialysis programs, and (iv) a lack of structured, objective information on renal replacement therapies for patients with advanced chronic kidney disease (CKD). We propose a number of pragmatic initiatives that could be simultaneously enacted to improve the situation in three areas: (i) the provision of objective information on renal replacement therapies for patients with advanced CKD, (ii) wider authorization of home dialysis networks and (iii) price increases in favour of home dialysis procedures.

摘要

2019 年冠状病毒病(COVID-19)大流行引起的卫生危机对法国的透析患者产生了重大影响。在 COVID-19 疫情的第一波中,透析患者急性呼吸综合征冠状病毒 2(SARS-CoV-2)感染的发病率为 3.3%-是普通人群的 13 倍。相应的死亡率很高,达到 21%。截至 2021 年 4 月 19 日,法国透析患者 SARS-CoV-2 感染的累积患病率为 14%。来自法国、意大利、英国和加拿大的趋同科学数据表明,家庭透析将 SARS-CoV-2 感染的风险降低了至少两倍。不幸的是,法国的家庭透析发展不足:在家中接受治疗的透析患者比例仅为 7%。法国为终末期肾病患者提供家庭护理的障碍包括:(i)家庭血液透析和辅助腹膜透析(PD)护士访问的不利定价政策;(ii)肾科医生在家透析培训不足;(iii)家庭透析计划的行政授权数量较少;(iv)缺乏针对晚期慢性肾脏病(CKD)患者的肾脏替代疗法的结构化、客观信息。我们提出了一些务实的倡议,可以同时在三个方面改善现状:(i)为晚期 CKD 患者提供关于肾脏替代疗法的客观信息;(ii)扩大家庭透析网络的授权范围;(iii)有利于家庭透析程序的价格上涨。

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