从红树林内生真菌 S30 中分离得到的两种新的 2,5-二酮哌嗪衍生物。
Two new 2,5-diketopiperazine derivatives from mangrove-derived endophytic fungus S30.
机构信息
Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, Hainan, China.
Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University, Haikou, Hainan, China.
出版信息
Nat Prod Res. 2022 Jul;36(14):3651-3656. doi: 10.1080/14786419.2021.1878168. Epub 2021 Feb 1.
Two new 2,5-diketopiperazines derivatives (), together with eight known analogs (), were isolated from a culture broth of an endophytic fungus S30, derived from mangrove . Their complete structures were determined by a detailed analysis of spectroscopic data and ECD calculations. The antimicrobial activity and neuroprotective activity of these isolated compounds were also evaluated.
两种新的 2,5-二酮哌嗪衍生物（），以及八种已知类似物（），从红树林内生真菌 S30 的发酵液中分离得到。通过详细的光谱数据分析和 ECD 计算确定了它们的完整结构。还评估了这些分离化合物的抗菌活性和神经保护活性。
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