Kanthasamy Kavin A, Akshintala Venkata S, Singh Vikesh K
Division of Gastroenterology, Johns Hopkins Medical Institutions, 1800 Orleans Street, Baltimore, MD 21287, USA.
1800 Orleans Street, Sheikh Zayed Tower, Baltimore, MD 21287, USA.
Gastroenterol Clin North Am. 2021 Mar;50(1):141-150. doi: 10.1016/j.gtc.2020.10.014. Epub 2020 Dec 23.
Acute pancreatitis (AP) remains among the most common gastrointestinal disorders leading to hospital admission. Optimizing nutritional support and maintaining gut function is instrumental in recovery of patients with AP. Enteral nutrition remains one of the only interventions with demonstrated mortality benefit in AP largely through preservation of gut function, serving to preserve the gut barrier as means to mitigate immune dysregulation and systemic inflammation inherent to AP. Practice variation remains in timing, route, and composition of nutritional support. This review highlights contemporary evidence regarding optimal nutritional support in AP and provides recommendations for management in line with current consensus opinions.
急性胰腺炎（AP）仍然是导致住院的最常见胃肠道疾病之一。优化营养支持和维持肠道功能对AP患者的康复至关重要。肠内营养仍然是少数几种已证明对AP患者有降低死亡率作用的干预措施之一，主要是通过维持肠道功能，保护肠道屏障，从而减轻AP固有的免疫失调和全身炎症。在营养支持的时机、途径和组成方面仍存在实践差异。本综述重点介绍了关于AP最佳营养支持的当代证据，并根据当前的共识意见提供了管理建议。
