Kibaru Joyce, Kotecha Pinky, Iya Abdulkarim Muhammad, Russell Beth, Abdullahi Muzzammil, Alhassan Sani Usman, Mustapha Muhammad Inuwa, Bryan Richard T, Van Hemelrijck Mieke
Faculty of Life Sciences and Medicine, Translational Oncology and Urology Research, King's College London, London, UK
Faculty of Life Sciences and Medicine, Translational Oncology and Urology Research, King's College London, London, UK.
BMJ Open. 2021 Jan 31;11(1):e041894. doi: 10.1136/bmjopen-2020-041894.
Bladder cancer (BC) is the 10th common cancer worldwide and ranks seventh in Nigeria. This scoping review aims to identify the gaps in clinical care and research of BC in Nigeria as part of the development of a larger national research programme aiming to improve outcomes and care of BC.
This review will be conducted according to Arksey and O'Malley scoping review methodology framework. The following electronic databases will be searched: Medline (using the PubMed interface), Ovid Gateway (Embase and Ovid), Cochrane library and Open Grey literature. Two independent reviewers will screen titles and abstracts and subsequently screen full-text studies for inclusion, any lack of consensus will be discussed with a third reviewer. Any study providing insight into the epidemiology or treatment pathway of BC (RCTs, observations, case series, policy paper) will be included. A data chart will be used to extract relevant data from the included studies. Results will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews. A consultation process will be carried out with a multidisciplinary team of Nigerian healthcare professionals, patients and scientists.
The results will be disseminated through peer-reviewed publications. By highlighting the key gaps in the literature, this review can provide direction for future research and clinical guidelines in Nigeria (and other low-income and middle-income countries), where BC is more prevalent due to local risk factors and healthcare settings.
膀胱癌（BC）是全球第10大常见癌症，在尼日利亚排名第七。本综述旨在识别尼日利亚膀胱癌临床护理和研究中的差距，作为旨在改善膀胱癌治疗效果和护理的更大规模国家研究计划的一部分。
本综述将根据阿克西和奥马利的综述方法框架进行。将检索以下电子数据库：Medline（使用PubMed界面）、Ovid网关（Embase和Ovid）、Cochrane图书馆和开放灰色文献。两名独立评审员将筛选标题和摘要，随后筛选全文研究以确定纳入情况，任何存在的共识缺乏将与第三名评审员讨论。任何提供膀胱癌流行病学或治疗途径见解的研究（随机对照试验、观察性研究、病例系列、政策文件）都将被纳入。将使用数据图表从纳入的研究中提取相关数据。结果将根据系统评价和荟萃分析扩展的首选报告项目进行报告，以进行综述。将与尼日利亚医疗保健专业人员、患者和科学家的多学科团队开展咨询过程。
研究结果将通过同行评审出版物进行传播。通过突出文献中的关键差距，本综述可为尼日利亚（以及其他低收入和中等收入国家）未来的研究和临床指南提供方向，在这些国家，由于当地风险因素和医疗环境，膀胱癌更为普遍。
