Mungadi I A, Malami S A
Department of Surgery, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
West Afr J Med. 2007 Jul-Sep;26(3):226-9. doi: 10.4314/wajm.v26i3.28315.
An unusually high prevalence of bladder cancer was noticed by clinicians and in the cancer registry of Usmanu Danfodiyo University Teaching Hospital, Sokoto. Several areas of this region were also known to be endemic for urinary schistosomiasis.
To determine the epidemiological characteristics of bladder cancer in the region and to assess the impact of schistosomiasis on these cases.
Retrospective review of clinical and histopathogical records of bladder cancer cases seen at Usmanu Danfodiyo University Teaching Hospital, Sokoto from January 1999 to December 2004.
One hundred and thirty three cases satisfied our criteria for inclusion. There was a 4.7 fold rise in the number of bladder cancer cases between 1999 and 2004. The male to female ratio was 11.1:1.0. The mean age was 46.0 years and ranged from 20 to 82 years. Majority, 107 (80.5%) were farmers and fishermen from regions of the distribution of surrounding river or their smaller tributaries. Squamous Cell Carcinoma comprised 65.1% of histologically verified cases and in 50% of Squamous Cell Carcinoma; there was histological evidence of chronic urinary schistosomiasis.
Bladder cancer is a common malignancy in Sokoto, North-Western Nigeria. The association with chronic urinary schistosomiasis is very strong and the hospital incidence appears to be rising.
索科托乌斯曼努·丹福迪奥大学教学医院的临床医生和癌症登记处注意到膀胱癌的患病率异常高。该地区的几个地方也被认为是泌尿血吸虫病的流行区。
确定该地区膀胱癌的流行病学特征，并评估血吸虫病对这些病例的影响。
回顾性分析1999年1月至2004年12月在索科托乌斯曼努·丹福迪奥大学教学医院就诊的膀胱癌病例的临床和组织病理学记录。
133例符合纳入标准。1999年至2004年间，膀胱癌病例数增长了4.7倍。男女比例为11.1:1.0。平均年龄为46.0岁，范围在20至82岁之间。大多数患者，即107例（80.5%）是来自周边河流或其较小支流分布区域的农民和渔民。鳞状细胞癌占组织学确诊病例的65.1%，在50%的鳞状细胞癌病例中，有慢性泌尿血吸虫病的组织学证据。
膀胱癌是尼日利亚西北部索科托的一种常见恶性肿瘤。与慢性泌尿血吸虫病的关联非常密切，且医院发病率似乎在上升。
