巴西 15 年未确诊的寻常狼疮型皮肤结核病例。

A case of tuberculosis verrucosa cutis in Brazil undiagnosed for 15 years.

机构信息

University of São Paulo, Medical School, Clinics Hospital, São Paulo, SP, Brazil.

São Paulo State University (UNESP), Institute of Biosciences, São Vicente, SP, Brazil; São Paulo State University (UNESP), Institute for Advanced Studies of Ocean, São Vicente, SP, Brazil.

出版信息

Braz J Infect Dis. 2021 May-Jun;25(3):101593. doi: 10.1016/j.bjid.2021.101593. Epub 2021 Jul 6.

DOI:10.1016/j.bjid.2021.101593

PMID:34242596

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9392159/

Abstract

Tuberculosis verrucosa cutis is a rare medical condition that is caused by the inoculation of Mycobacterium tuberculosis into the skin of a previously sensitized individual. This clinical form of tuberculosis corresponds to 1-2% of all cases of tuberculosis and due to the paucibacillary characteristic of the lesions, patients can be misdiagnosed, accounting for the chronification of the skin infection. Herein, we report the case of a 26-year-old male farmer, presenting plaques with verrucosa and hyperkeratosis features in the left thigh and buttocks during 15 years. M. tuberculosis was identified by PCR and the patient was treated with standard anti-tuberculosis drugs, with subsequent improvement of the skin lesions.

摘要

寻常狼疮是一种罕见的皮肤疾病，由结核分枝杆菌接种到曾致敏个体的皮肤中引起。这种临床形式的结核占所有结核病例的 1-2%，由于病变的少菌性特征，患者可能会被误诊，导致皮肤感染的慢性化。在此，我们报告了一例 26 岁男性农民的病例，他在 15 年间左大腿和臀部出现疣状和角化过度的斑块。通过 PCR 鉴定出结核分枝杆菌，患者接受了标准抗结核药物治疗，随后皮肤病变得到改善。