Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, China.
Neurosurgical Institute of Fudan University, China.
Oxid Med Cell Longev. 2021 Jan 13;2021:5653948. doi: 10.1155/2021/5653948. eCollection 2021.
Magnetic resonance imaging (MRI) is widely used for the evaluation of moyamoya disease (MMD). In this paper, we describe the features of time-of-flight magnetic resonance angiography (TOF-MRA) and susceptibility-weighted imaging (SWI) at 7 T in a series of MMD patients. In this prospective pilot study, 7 patients (median age: 45.6 years; range: 30-52 years) with MMD and no contraindications for MRI underwent T2-weighted, SWI, and TOF-MRA sequences using a research 7 T head-only scanner. We show that such sequences at ultrahigh field (UHF) represent new and valuable approaches to unravel and characterize MMD. While SWI reveals more remarkable imaging signs related to an improved magnitude and phase contrast imaging, the collateral network pathways in MMD could be excellently delineated using 7 T TOF-MRA. In particular, using SWI and MRA fusion images in UHF MRI helps to improve the detection of bleeding points in hemorrhagic MMD. Our findings indicate that ultrahigh field MRI is very promising to access the severity of the disease and may facilitate revascularization surgery of MMD patients.
磁共振成像（MRI）广泛用于烟雾病（MMD）的评估。在本文中，我们描述了一系列 MMD 患者在 7T 时的磁共振血管成像（TOF-MRA）和磁敏感加权成像（SWI）的特征。在这项前瞻性的初步研究中，7 名（中位年龄：45.6 岁；范围：30-52 岁）无 MRI 禁忌证的 MMD 患者使用研究用 7T 头-only 扫描仪接受了 T2 加权、SWI 和 TOF-MRA 序列。我们表明，这种超高磁场（UHF）的序列是揭示和描述 MMD 的新的有价值的方法。虽然 SWI 显示出与改进的幅度和相位对比成像相关的更显著的成像迹象，但 7T TOF-MRA 可以极好地描绘 MMD 中的侧支网络途径。特别是，在 UHF MRI 中使用 SWI 和 MRA 融合图像有助于提高对出血性 MMD 中出血点的检测。我们的发现表明超高磁场 MRI 非常有希望评估疾病的严重程度，并可能有助于 MMD 患者的血运重建手术。
