Alawad Awad Ali, Ibrahim Rashid, Nawara Hossam, Kheder Adel, Abounozha Sabry
University of Medical Sciences and Technology, Khartoum, Sudan.
University Hospitals Plymouth NHS Trust, Plymouth, UK.
Ann Med Surg (Lond). 2020 Dec 26;62:95-97. doi: 10.1016/j.amsu.2020.12.039. eCollection 2021 Feb.
A best evidence topic has been constructed using a described protocol. The three-part question addressed was: is breast-conserving surgery feasible after neoadjuvant chemotherapy for locally advanced breast cancer? Using the reported search, 19 articles were found, out of these 6 studies were deemed to be suitable to answer the question. The outcomes assessed were local recurrence rate. The best evidence showed that breast conserving surgery is safe in terms of local recurrence.
一个最佳证据主题已根据所述方案构建。所涉及的三部分问题是:新辅助化疗后对局部晚期乳腺癌进行保乳手术是否可行?通过报告的检索,共找到19篇文章,其中6项研究被认为适合回答该问题。评估的结果是局部复发率。最佳证据表明,就局部复发而言,保乳手术是安全的。