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佛罗里达州糖尿病前期患病率的地理差异、决定因素及时间变化

Geographic disparities, determinants, and temporal changes in the prevalence of pre-diabetes in Florida.

作者信息

Lord Jennifer, Roberson Shamarial, Odoi Agricola

机构信息

Biomedical and Diagnostic Sciences, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN, United States of America.

Florida Department of Health, Tallahassee, FL, United States of America.

出版信息

PeerJ. 2021 Jan 13;9:e10443. doi: 10.7717/peerj.10443. eCollection 2021.

Abstract

BACKGROUND

Left unchecked, pre-diabetes progresses to diabetes and its complications that are important health burdens in the United States. There is evidence of geographic disparities in the condition with some areas having a significantly high risks of the condition and its risk factors. Identifying these disparities, their determinants, and changes in burden are useful for guiding control programs and stopping the progression of pre-diabetes to diabetes. Therefore, the objectives of this study were to investigate geographic disparities of pre-diabetes prevalence in Florida, identify predictors of the observed spatial patterns, as well as changes in disease burden between 2013 and 2016.

METHODS

The 2013 and 2016 Behavioral Risk Factor Surveillance System data were obtained from the Florida Department of Health. Counties with significant changes in the prevalence of the condition between 2013 and 2016 were identified using tests for equality of proportions adjusted for multiple comparisons using the Simes method. Flexible scan statistics were used to identify significant high prevalence geographic clusters. Multivariable regression models were used to identify determinants of county-level pre-diabetes prevalence.

RESULTS

The state-wide age-adjusted prevalence of pre-diabetes increased significantly ( ≤ 0.05) from 8.0% in 2013 to 10.5% in 2016 with 72% (48/67) of the counties reporting statistically significant increases. Significant local geographic hotspots were identified. High prevalence of pre-diabetes tended to occur in counties with high proportions of non-Hispanic black population, low median household income, and low proportion of the population without health insurance coverage.

CONCLUSIONS

Geographic disparities of pre-diabetes continues to exist in Florida with most counties reporting significant increases in prevalence between 2013 and 2016. These findings are critical for guiding health planning, resource allocation and intervention programs.

摘要

背景

若不加以控制,糖尿病前期会发展为糖尿病及其并发症,而糖尿病及其并发症是美国重要的健康负担。有证据表明,这种疾病存在地理差异,一些地区患该疾病及其风险因素的风险显著较高。识别这些差异、其决定因素以及负担变化,有助于指导控制计划并阻止糖尿病前期发展为糖尿病。因此,本研究的目的是调查佛罗里达州糖尿病前期患病率的地理差异,确定观察到的空间模式的预测因素,以及2013年至2016年期间疾病负担的变化。

方法

2013年和2016年行为风险因素监测系统的数据来自佛罗里达州卫生部。使用经西姆斯方法调整用于多重比较的比例相等性检验,确定2013年至2016年期间该疾病患病率有显著变化的县。灵活扫描统计用于识别显著的高患病率地理集群。多变量回归模型用于确定县级糖尿病前期患病率的决定因素。

结果

全州年龄调整后的糖尿病前期患病率从2013年的8.0%显著增加(≤0.05)至2016年的10.5%,72%(48/67)的县报告有统计学显著增加。识别出了显著的局部地理热点地区。糖尿病前期的高患病率往往出现在非西班牙裔黑人人口比例高、家庭收入中位数低以及无医疗保险覆盖人口比例低的县。

结论

佛罗里达州糖尿病前期的地理差异仍然存在,大多数县报告2013年至2016年期间患病率显著增加。这些发现对于指导健康规划、资源分配和干预计划至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8ae/7811289/aca3fd665c10/peerj-09-10443-g001.jpg

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