重症新型冠状病毒肺炎感染中的急性出血性白质脑炎（赫斯特病）
Acute haemorrhagic leukoencephalitis (Hurst disease) in severe COVID- 19 infection.
作者信息
Haqiqi Ala, Samuels Theophilus Luke, Lamb Fiona Jillian, Moharrum Tamir, Myers Alice Elizabeth
机构信息
Department of Critical Care Medicine, East Surrey Hospital, Surrey and Sussex Healthcare NHS Trust, Redhill, United Kingdom.
Department of Radiology, Surrey and Sussex Healthcare NHS Trust, Redhill, United Kingdom.
出版信息
Brain Behav Immun Health. 2021 Mar;12:100208. doi: 10.1016/j.bbih.2021.100208. Epub 2021 Jan 23.
Coronavirus Disease 2019 (COVID-19) is well documented as a cause of respiratory tract infection. Increasingly, multi-systemic effects, including COVID-19-related neurologic features, are being reported. Here we report, what we believe to be, the first reported case of acute haemorrhagic leukoencephalitis (AHLE) with presence of oligoclonal bands in the cerebrospinal fluid. AHLE is a rare fulminant demyelinating disease, associated with severe COVID-19 infection.
2019冠状病毒病（COVID-19）作为呼吸道感染的病因已有充分记录。越来越多的多系统影响，包括与COVID-19相关的神经学特征，也不断被报道。在此，我们报告了我们认为的首例脑脊液中存在寡克隆带的急性出血性白质脑炎（AHLE）病例。AHLE是一种罕见的暴发性脱髓鞘疾病，与严重的COVID-19感染有关。
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