Kar Supratik, Leszczynski Jerzy
Interdisciplinary Center for Nanotoxicity, Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Jackson, MS 39217, USA.
Innovation (Camb). 2020 Aug 28;1(2):100021. doi: 10.1016/j.xinn.2020.100021. Epub 2020 Jul 31.
There is a strong risk of mutations in the genome sequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in animals. Consequently, a possibility of zoonotic transfer of a much stronger form of the present virus from animal to human is also very feasible in the near future. Thus, recent incidents of SARS-CoV-2 infection in animals need to be studied very carefully to protect against any future transmissions. Interspecies analysis from animal to human or vice versa is the tool of choice at the present time for understanding zoonotic transfer and improving/accelerated drug discovery for COVID-19.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）在动物基因组序列中发生突变的风险很大。因此，在不久的将来，目前这种病毒的更强形式从动物向人类进行人畜共患传播的可能性也非常大。因此，需要非常仔细地研究动物中最近发生的SARS-CoV-2感染事件，以防止未来的任何传播。目前，从动物到人类或反之的种间分析是了解人畜共患传播以及改进/加速COVID-19药物研发的首选工具。
