Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations.
作者信息
Dron Jacqueline S, Wang Minxian, Patel Aniruddh P, Kartoun Uri, Ng Kenney, Hegele Robert A, Khera Amit V
机构信息
Robarts Research Institute (J.S.D., R.A.H.), Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Department of Biochemistry (J.S.D., R.A.H.), Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
出版信息
Circ Genom Precis Med. 2021 Feb;14(1):e003182. doi: 10.1161/CIRCGEN.120.003182. Epub 2021 Feb 1.
Abstract
摘要
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The UK Biobank resource with deep phenotyping and genomic data.英国生物银行资源库，具有深度表型和基因组数据。
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Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.载脂蛋白 LPA 变异与冠心病风险的关联及对脂蛋白(a)降低治疗的意义：一项孟德尔随机分析。
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Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.连锁不平衡建模提高了多基因风险评分的准确性。
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