Department of Radiation Oncology, Seoul National University Hospital, Seoul, Korea.
Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
J Appl Clin Med Phys. 2021 Mar;22(3):86-93. doi: 10.1002/acm2.13181. Epub 2021 Feb 1.
We investigated the correlation between optical surface imaging using a three-dimensional (3D) scanner and magnetic resonance imaging (MRI) for suggesting feasibility in the clinical process of tracking volume changes in head and neck patients during radiation treatment.
Ten patients were divided into two groups depending on the location of their tumor (i.e., right or left side). With weekly imaging data, the change in volume based on MRI was evaluated during the treatment course. Four volumes of interest (VOIs) were calculated on the 3D surface image of the facial and cervical areas using an optical 3D scanner, and the correlation between volumetric parameters were analyzed.
The target volume changed significantly overall for both groups. The changes parotid volume reduced by up to 3.8% and 28.0% for groups A (right side) and B (left side), respectively. In Group A, VOI 1 on the facial area and VOI 3 on the cervical area decreased gradually during the treatment course by up to 3.3% and 10.7%, respectively. In Group B, only VOI 4 decreased gradually during the treatment course and reduced by up to 9.2%. In group A, the change in target volume correlated strongly with right-side parotid, VOI 1, and VOI 3, respectively. The parotid also showed strong correlations with VOIs (P < 0.01). The weight loss was strongly correlated with either PTV or parotid without statistical significance (P > 0.05). In group B (left side), the change in target volume correlated strongly with each volumetric parameter, including weight loss. For individual patient, PTV showed more correlation with VOIs on the cervical area than VOIs on the facial area.
An optical 3D scanner can be applied to track changes in volume without radiation exposure during treatment and the optical surface image correlated with MRI.
我们研究了使用三维（3D）扫描仪的光学表面成像与磁共振成像（MRI）之间的相关性，以探讨其在头颈部患者放射治疗过程中跟踪肿瘤体积变化的临床应用中的可行性。
根据肿瘤位置（右侧或左侧），将 10 名患者分为两组。通过每周的影像数据，评估治疗过程中基于 MRI 的体积变化。使用光学 3D 扫描仪对面部和颈部区域的 3D 表面图像计算四个感兴趣区域（VOI），并分析体积参数之间的相关性。
两组患者的靶区体积均有显著变化。腮腺体积变化最大，左侧腮腺体积减少 28.0%，右侧腮腺体积减少 3.8%。在左侧腮腺组 A 中，面部区域的 VOI 1 和颈部区域的 VOI 3 在治疗过程中逐渐减少，分别减少了 3.3%和 10.7%。在右侧腮腺组 B 中，只有 VOI 4 在治疗过程中逐渐减少，减少了 9.2%。在组 A 中，靶区体积的变化与右侧腮腺、VOI 1 和 VOI 3 分别呈强烈相关。腮腺与 VOI 之间也存在强烈的相关性（P<0.01）。体重减轻与 PTV 或腮腺之间呈强烈相关，但无统计学意义（P>0.05）。在左侧腮腺组 B 中，靶区体积的变化与包括体重减轻在内的所有体积参数均呈强烈相关。对于个别患者，PTV 与颈部区域的 VOI 相关性高于面部区域的 VOI。
光学 3D 扫描仪可在治疗过程中无辐射暴露的情况下用于跟踪体积变化，并且光学表面图像与 MRI 相关。
