Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Laser Unit, Division of Dermatology, Rabin Medical Center, Petah-Tiqva, Israel.
J Cosmet Dermatol. 2021 Jun;20(6):1679-1683. doi: 10.1111/jocd.13958. Epub 2021 Feb 1.
Laser treatments for facial rejuvenation are common, with ablative modalities being of more common use for this indication. Efficient nonablative modalities are of rising demand.
Our aim was to determine the safety and efficacy of high-fluence, nonablative 1540-nm fractional Erbium:glass laser for facial rejuvenation.
A retrospective study of patients treated with 3-4 treatments using the 1540-nm fractional Erbium:glass laser for facial rejuvenation, using 2500-3000 mJ/stacked pulses (51-61 mJ per pixel). Patients were followed-up for 3 months following their last treatment. Before and after photos were independently blindly evaluated by 2 dermatologists, who graded them using a scale from 0 (exacerbation) to 4 (76%-100% improvement) for 2 different facial regions (frontal face region and lateral canthal region). Pain perception and adverse effects as well as patient satisfaction were documented throughout the study.
Sixteen patients completed both treatment and follow-up period. At the 3-months posttreatment follow-up visit, moderate-to-significant improvement in rhytids appearance (mean grade of improvement: 2.93 for frontal face and 3 for lateral canthal region) was observed. Patients' satisfaction was high (4.25). Patients reported mild and transient erythema posttreatment with no other adverse effects.
The high-fluence 1540-nm fractional Erbium:glass laser is a safe and effective nonablative modality for facial rejuvenation.
激光面部年轻化治疗很常见，其中消融模式在该适应证中更为常用。高效的非消融模式需求日益增长。
我们旨在确定高能量、非消融性 1540nm 铒玻璃激光在面部年轻化中的安全性和有效性。
对 16 例接受 3-4 次 1540nm 分束铒玻璃激光治疗的患者进行回顾性研究，使用 2500-3000mJ/叠加脉冲（每个像素 51-61mJ）。患者在最后一次治疗后 3 个月接受随访。2 位皮肤科医生独立盲评治疗前后的照片，使用 0（恶化）至 4（76%-100%改善）的评分标准对 2 个不同的面部区域（额面部和外眦区域）进行评分。在整个研究过程中记录疼痛感知和不良反应以及患者满意度。
16 例患者完成了治疗和随访。在治疗后 3 个月的随访中，观察到皱纹外观有中度至显著改善（额面部的平均改善评分：2.93，外眦区域为 3）。患者满意度较高（4.25）。患者报告治疗后有轻度和短暂的红斑，无其他不良反应。
高能量 1540nm 分束铒玻璃激光是一种安全有效的非消融性面部年轻化治疗方法。
