Toledano Michel
Continuum (Minneap Minn). 2021 Feb 1;27(1):93-120. doi: 10.1212/CON.0000000000000930.
This article reviews infectious etiologies of spinal cord dysfunction, emphasizing the importance of recognizing common clinicoradiographic syndromes and interpreting them in the context of exposure risk and individual host susceptibilities.
This article discusses the shifting spectrum of neurologic infectious diseases, the growing population of patients who are immunocompromised, and the emergence of effective antiretroviral therapies. In addition, it discusses new molecular and serologic tests that have the potential to enhance our ability to rapidly and accurately diagnose infectious diseases of the spine.
When evaluating patients with suspected infectious myelopathies, it is imperative to narrow the range of pathogens under consideration. The geography, seasonality, and clinicoradiographic presentation and immunocompetence status of the patient define the range of potential pathogens and should guide testing and initial management.
本文回顾脊髓功能障碍的感染性病因，强调识别常见临床影像学综合征并结合暴露风险和个体宿主易感性进行解读的重要性。
本文讨论了神经感染性疾病谱的变化、免疫功能低下患者群体的增加以及有效抗逆转录病毒疗法的出现。此外，还讨论了新的分子和血清学检测方法，这些方法有可能提高我们快速准确诊断脊柱感染性疾病的能力。
在评估疑似感染性脊髓病患者时，必须缩小所考虑病原体的范围。患者的地理位置、季节因素、临床影像学表现和免疫功能状态决定了潜在病原体的范围，应指导检测和初始治疗。
