University Hospital Complex Professor Edgard Santos, Federal University of Bahia, and Medicine and Health Postgraduate Program University Federal of Bahia, Salvador, Brazil.
Department of Nutrition, Nutrition School of Federal University of Bahia, Salvador, Brazil.
Metab Syndr Relat Disord. 2021 May;19(4):233-239. doi: 10.1089/met.2020.0064. Epub 2021 Feb 1.
Diabetes mellitus (DM) is associated with a higher prevalence of metabolic syndrome (MS) and cardiovascular mortality. However, few Brazilian studies evaluated MS in diabetic individuals with cardiovascular disease (CVD). Nevertheless, the objective of this study was to compare the prevalence of MS in cardiac patients with and without DM. Cross-sectional study of BALANCE Program Trial with patients with CVD, ≥45 years old, who had been attending specialized ambulatories on cardiovascular health, in eight states in the Northeast of Brazil. The components of MS were evaluated by following the criteria of National Cholesterol Education Program's Adult Treatment Panel III (NCEP ATP III) and Joint Interim Statement (JIS). In addition, there were investigated different indexes of abdominal obesity, variables related to lifestyle, and food intake. The statistical analysis included descriptive statistics and the Student's -test, Mann-Whitney, and chi-squared tests for the comparison of groups. There were significant values of < 0.05. Six hundred forty-seven individuals were evaluated with average (standard deviation) age of 63.1 (9.3) years, being 50.5% females and 40.3% diabetic patients. When the groups of patients who were diabetic and the nondiabetic ones, the first showed higher percentage of obesity (38.5% vs. 23.2%, < 0.001), of high waist circumference (84.8% vs. 71.9%; < 0.001), higher waist-height ratio [0.6 (0.6-0.7) vs. 0.6 (0.5-0.6); < 0.001], conicity index [1.35 (1.29-1.39) vs. 1.32 (1.27-1.38); = 0.004], and prevalence of MS, because of the criteria of NCEP ATP III (98.8% vs. 80.4%; < 0.001), as well as the criteria of JIS (99.2% vs. 89.3%; < 0.001). The component of higher frequency was high blood pressure and/or hypertension (95.0%), followed by hypertriglyceridemia (93.0%). There were no differences regarding age, lifestyle, and food intake. Diabetic individuals with CVD showed more prevalence of MS and more abdominal obesity than nondiabetic individuals. ClinicalTrials.gov ID: NCT01620398.
糖尿病（DM）与代谢综合征（MS）和心血管死亡率的患病率较高相关。然而，很少有巴西研究评估过患有心血管疾病（CVD）的糖尿病患者中的 MS。然而，本研究的目的是比较有和没有 DM 的心脏病患者中 MS 的患病率。
这是 BALANCE 计划试验的一项横断面研究，参与者为患有 CVD、年龄≥45 岁的患者，他们一直在巴西东北部八个州的心血管保健专科门诊就诊。通过遵循国家胆固醇教育计划成人治疗专家组 III（NCEP ATP III）和联合临时声明（JIS）的标准来评估 MS 的组成部分。此外，还研究了不同的腹部肥胖指标、与生活方式和饮食相关的变量。统计分析包括描述性统计和学生 t 检验、Mann-Whitney 检验和卡方检验，用于组间比较。有显著性差异的 P 值 < 0.05。
共评估了 647 名患者，平均（标准差）年龄为 63.1（9.3）岁，其中 50.5%为女性，40.3%为糖尿病患者。当比较糖尿病和非糖尿病患者的两组时，前者显示出更高的肥胖率（38.5%比 23.2%， < 0.001）、更高的高腰围率（84.8%比 71.9%； < 0.001）、更高的腰围-身高比[0.6（0.6-0.7）比 0.6（0.5-0.6）； < 0.001]、更大的锥度指数[1.35（1.29-1.39）比 1.32（1.27-1.38）； = 0.004]，以及 NCEP ATP III 标准下的 MS 患病率更高（98.8%比 80.4%； < 0.001），以及 JIS 标准下的 MS 患病率更高（99.2%比 89.3%； < 0.001）。更高频率的成分是高血压和/或高血压（95.0%），其次是高三酰甘油血症（93.0%）。两组在年龄、生活方式和饮食方面没有差异。患有 CVD 的糖尿病患者比非糖尿病患者 MS 和腹部肥胖的患病率更高。临床试验.gov 标识符：NCT01620398。
