Elwany S, Kamel T
Department of Otolaryngology, Dr. Fakhry Hospital, Alkhobar, Saudi Arabia.
Laryngoscope. 1988 Apr;98(4):386-9. doi: 10.1288/00005537-198804000-00005.
The present investigation examines the effects of sickle cell crisis on peripheral auditory function and auditory brainstem response (ABR). The study includes 10 homozygous sickle cell anemia patients with documented sickle cell (SS) hemoglobin. Testing was performed during the crisis and 1 month after it subsided. Unilateral high frequency hearing loss was found in three patients but persisted in only one of them. Abnormal ABR tracings occurred in four patients but reversed to normal in one of them. The study suggests a trend toward increased incidence of sensorineural hearing loss (SNHL) and ABR changes as frequency and severity of crisis episodes increases. The relationship between SNHL and ABR is analyzed and discussed.
本研究调查了镰状细胞危象对外周听觉功能和听觉脑干反应（ABR）的影响。该研究纳入了10名记录有镰状细胞（SS）血红蛋白的纯合子镰状细胞贫血患者。在危象期间及危象消退1个月后进行了测试。3名患者出现单侧高频听力损失，但仅1名患者的听力损失持续存在。4名患者的ABR描记异常，但其中1名患者的ABR恢复正常。该研究表明，随着危象发作的频率和严重程度增加，感音神经性听力损失（SNHL）和ABR变化的发生率有上升趋势。对SNHL与ABR之间的关系进行了分析和讨论。
