Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Medizinische Hochschule Hannover, Germany.
Institut für Diagnostische und Interventionelle Neuroradiologie, Medizinische Hochschule Hannover, Germany.
Laryngorhinootologie. 2021 Feb;100(2):99-103. doi: 10.1055/a-1286-5059. Epub 2021 Feb 1.
Inverted papilloma of middle ear is an extremely rare lesion of the respiratory epithelium that normally occurs in the nasal cavity and paranasal sinuses. So far less than 17 cases were described in literature. A 45-year-old patient was admitted in our Department with hearing loss, otorrhea and pulsing tinnitus on the right ear. The clinical examination showed a granulation tissue on the right eardrum. No tumor formation was seen in the nasal cavity. The MRI showed a tissue formation in the tympanic cavity with an extension in the middle cranial fossa. A mastoidectomy with antrotomy and duraplasty was performed. The histological diagnosis was inverted papilloma of the middle ear. In a second step occurred an eradication of the tumor with a subtotal petrosectomy. The etiology of the inverted papilloma of the middle ear is unknown. Our case is so far the 18 case described.Our experience has shown that the eradication of the tumor with a subtotal petrosectomy resulted as reasonable procedure. A long-term follow-up is suggested in order to detect possible recurrence or malignant transformation.
中耳内翻性乳头状瘤是一种极为罕见的呼吸道上皮病变，通常发生在鼻腔和鼻窦。到目前为止，文献中仅描述了不到 17 例。一位 45 岁的患者因右耳听力下降、耳漏和搏动性耳鸣到我科就诊。临床检查显示右鼓膜有肉芽组织。鼻腔内未见肿瘤形成。MRI 显示鼓室中有组织形成，并延伸至中颅窝。行乳突切开术和硬脑膜成形术。组织学诊断为中耳内翻性乳头状瘤。第二步是进行部分颞骨切除术以彻底清除肿瘤。中耳内翻性乳头状瘤的病因尚不清楚。我们的病例是迄今为止第 18 例。我们的经验表明，部分颞骨切除术彻底清除肿瘤是一种合理的治疗方法。建议进行长期随访，以检测可能的复发或恶性转化。
