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使用表面线圈核磁共振波谱法在体内无创测量31P代谢物的摩尔浓度。

Noninvasive measurement of molar concentrations of 31P metabolites in vivo, using surface coil NMR spectroscopy.

作者信息

Tofts P S, Wray S

机构信息

Institute of Neurology, London, United Kingdom.

出版信息

Magn Reson Med. 1988 Jan;6(1):84-6. doi: 10.1002/mrm.1910060109.

DOI:10.1002/mrm.1910060109
PMID:3352508
Abstract

The measurement of absolute concentration of 31P metabolites is described, using water 1H as an internal concentration standard. An analysis of the effect of variations in coil Q on flip angle and sensitivity is presented and verified experimentally. Concentrations of nucleoside triphosphate in rat brain and muscle have been measured.

摘要

描述了使用水1H作为内浓度标准来测量31P代谢物的绝对浓度。给出了线圈品质因数变化对翻转角和灵敏度影响的分析,并通过实验进行了验证。已测量了大鼠脑和肌肉中核苷三磷酸的浓度。

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Noninvasive measurement of molar concentrations of 31P metabolites in vivo, using surface coil NMR spectroscopy.使用表面线圈核磁共振波谱法在体内无创测量31P代谢物的摩尔浓度。
Magn Reson Med. 1988 Jan;6(1):84-6. doi: 10.1002/mrm.1910060109.
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Detection and quantitation of phosphorus metabolites in crude tissue extracts by 1H and 31P NMR: use of gradient assisted 1H-31P HMQC experiments, with selective pulses, for the assignment of less abundant metabolites.
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Quantitative in vivo magnetic resonance spectroscopy using synthetic signal injection.使用合成信号注入的定量活体磁共振波谱。
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Synthetic signal injection using inductive coupling.使用电感耦合的合成信号注入。
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