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与蜂花粉相比,蜂粮具有更高的抗菌潜力。

Bee Bread Exhibits Higher Antimicrobial Potential Compared to Bee Pollen.

作者信息

Pełka Karolina, Otłowska Olga, Worobo Randy W, Szweda Piotr

机构信息

Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology, ul. G. Narutowicza 11/12, 80-233 Gdańsk, Poland.

Department of Food Science, Cornell University, Ithaca, NY 14853, USA.

出版信息

Antibiotics (Basel). 2021 Jan 28;10(2):125. doi: 10.3390/antibiotics10020125.

Abstract

This study aimed at investigation of the antimicrobial potential of ethanolic extracts of bee bread (BB) and bee pollen (BP) and suspensions of these products in MHB (Mueller Hinton Broth). We covered 30 samples of BP and 19 samples of BB harvested in Polish apiaries. Slightly lower activity was observed against Gram-negative bacteria compared to Gram-positive staphylococci. BB extracts exhibited higher inhibitory potential with minimum inhibitory concentration (MIC) values in the range from 2.5 to 10% (/) against ATCC 25923 and ATCC 29213. Most active BB extracts, namely, BB6, BB11 and BB19, effectively inhibited growth of clinical isolates of ( = 9), including MRSA () strains ( = 3) at concentrations ranging from 2.5 to 5.0% (/). Minimal bactericidal concentration (MBC) values were in the same range of concentrations; however, a shift from 2.5 to 5.0% (/) was observed for some products. The most active BP extracts inhibited the growth of reference strains of at a concentration of 5% (/). Up to the concentration of 20% (/) three and seven BP extracts were not able to inhibit the growth of ATCC 29213 and ATCC 25923 respectively. The growth of staphylococci was also importantly inhibited in suspensions of the products in MHB. No correlation between phenolic content and antimicrobial activity was observed.

摘要

本研究旨在调查蜂粮(BB)和蜂花粉(BP)乙醇提取物及其在MHB( Mueller Hinton肉汤)中的悬浮液的抗菌潜力。我们采集了波兰养蜂场的30份BP样本和19份BB样本。与革兰氏阳性葡萄球菌相比,观察到对革兰氏阴性菌的活性略低。BB提取物表现出更高的抑制潜力,对ATCC 25923和ATCC 29213的最低抑菌浓度(MIC)值在2.5%至10%(/)范围内。最具活性的BB提取物,即BB6、BB11和BB19,在浓度为2.5%至5.0%(/)时有效抑制了9株临床分离株(包括3株耐甲氧西林金黄色葡萄球菌(MRSA)菌株)的生长。最小杀菌浓度(MBC)值在相同浓度范围内;然而,一些产品的浓度从2.5%变为5.0%(/)。最具活性的BP提取物在浓度为5%(/)时抑制了参考菌株的生长。在高达20%(/)的浓度下,分别有3份和7份BP提取物无法抑制ATCC 29213和ATCC 25923的生长。在产品在MHB中的悬浮液中,葡萄球菌的生长也受到了显著抑制。未观察到酚类含量与抗菌活性之间的相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3988/7911093/88cfadbac619/antibiotics-10-00125-g001.jpg

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