Yeung Andy Wai Kan, Tzvetkov Nikolay T, Arkells Nicolas, Milella Luigi, Stankiewicz Adrian M, Huminiecki Łukasz, Horbanczuk Olaf K, Atanasov Atanas G
Oral and Maxillofacial Radiology, Applied Oral Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China.
Institute of Molecular Biology "Roumen Tsanev", Department of Biochemical Pharmacology and Drug Design, Bulgarian Academy of Sciences, Sofia, Bulgaria.
J Cannabis Res. 2019 Jun 7;1(1):4. doi: 10.1186/s42238-019-0004-y.
Cannabis, cannabinoids and endocannabinoids are heavily investigated topics with many articles published every year. We aimed to identify the 100 most cited manuscripts among the vast literature and analyze their contents.
Web of Science (WoS) Core Collection was searched to identify the 100 most cited relevant manuscripts, which were analyzed with reference to (1) authorship, (2) institution, (3) country, (4) document type, (5) journal, (6) publication year, (7) WoS category, and (8) citation count. Semantic content and citation data of the manuscripts were analyzed with VOSviewer.
The most cited manuscripts were published between 1986 and 2016, with the majority being published in the 2000s (n = 51). The number of citations for the top 100 articles ranged from 469 to 3651, with a median citation count of 635.5. The most prolific authors were Vincenzo Di Marzo (n = 11) and Daniele Piomelli (n = 11). The major contributing countries were USA (n = 49), Italy (n = 22), UK (n = 19), and France (n = 11). The most prolific institutions were University of California (n = 14), National Research Council of Italy (n = 12) and National Institutes of Health USA (n = 12). The manuscripts consisted of original articles (n = 75), reviews (n = 24) and a note (n = 1). The most dominant journal was Nature (n = 15). The major WoS categories associated were Multidisciplinary sciences (n = 31), Neurosciences (n = 20), Pharmacology / Pharmacy (n = 16), and General / Internal Medicine (n = 11).
The top-ranked manuscripts among the 100 were concerning analgesia, weight loss, long-term potentiation, depolarization-induced suppression of inhibition, opiates and other topics. Cannabinoid type 1 (CB1) receptor was studied by more of the top 100 papers in comparison to cannabinoid type 2 (CB2) receptor. The most frequently mentioned chemicals in these publications were 2-arachidonoylglycerol, tetrahydrocannabinol, and anandamide. Together, these manuscripts comprise the most highly cited publications in the topic, literally the molecular neuroscience at its "high".
大麻、大麻素和内源性大麻素是研究热点，每年都有大量相关文章发表。我们旨在从海量文献中找出被引用次数最多的100篇手稿并分析其内容。
检索科学网（WoS）核心合集以确定被引用次数最多的100篇相关手稿，并从以下方面进行分析：（1）作者；（2）机构；（3）国家；（4）文献类型；（5）期刊；（6）出版年份；（7）WoS类别；（8）被引用次数。使用VOSviewer对手稿的语义内容和引用数据进行分析。
被引用次数最多的手稿发表于1986年至2016年之间，其中大部分发表于21世纪（n = 51）。前100篇文章的被引用次数在469次至3651次之间，中位数为635.5次。发文最多的作者是文森佐·迪·马尔佐（n = 11）和达尼埃莱·皮奥梅利（n = 11）。主要贡献国家为美国（n = 49）、意大利（n = 22）、英国（n = 19）和法国（n = 11）。发文最多的机构是加利福尼亚大学（n = 14）、意大利国家研究委员会（n = 12）和美国国立卫生研究院（n = 12）。这些手稿包括原创文章（n = 75）、综述（n = 24）和一篇注释（n = 1）。最具主导地位的期刊是《自然》（n = 15）。主要相关WoS类别为多学科科学（n = 31）、神经科学（n = 20）、药理学/药剂学（n = 16）和普通/内科学（n = 11）。
100篇排名靠前的手稿涉及镇痛、减肥、长时程增强、去极化诱导的抑制性抑制、阿片类药物及其他主题。与大麻素2型（CB2）受体相比，前100篇论文中更多地研究了大麻素1型（CB1）受体。这些出版物中最常提及 的化学物质是2-花生四烯酸甘油酯、四氢大麻酚和花生四烯乙醇胺。总之，这些手稿构成了该主题中被引用次数最多的出版物，堪称分子神经科学领域的“巅峰之作”。
