Laaboudi Fatima-Zahrae, Rejdali Mohamed, Salhi Amin, Elyoussfi Abedellah, Talhaoui Abdelmonaem, Amhamdi Hassan, Ahari M'hamed
Applied Chemistry Team, Department of Chemistry, Faculty of Sciences and Techniques of Al Hoceima, Abdelmalek Essaâdi University, Tetouan, Morocco.
Physical Chemistry of Natural Resources and Process Team, Laboratory of Applied Chemistry and Environment (LCAE), Department of Chemistry, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
Toxicol Rep. 2024 Aug 15;13:101713. doi: 10.1016/j.toxrep.2024.101713. eCollection 2024 Dec.
Beneficial cannabis use has sparked growing interest among researchers, leading to an increase in empirical studies exploring its phytochemistry and applications. However, understanding the overall research orientation remains limited. This study aims to bridge this gap by conducting a bibliometric analysis of 7841 documents published from 2012 to 2022. The analysis reveals an annual growth rate of 16.83 %, with a focus on medicine, pharmacology, toxicology, pharmaceutics, biochemistry, genetics, molecular biology, and neuroscience. Performance analysis highlights metrics of sources, countries, affiliations, and authors, while science mapping identifies keywords, thematic evolution, and citation/co-authorship patterns. Notably, Morocco, despite its limited initial contributions, has shown recent steady growth in cannabis research, with an annual growth rate of 14.31 % and a 51.72 % international collaborative rate. This study provides valuable insights into established fields and potential research directions in cannabis research, paving the way for a deeper understanding among the audience. With the changing legal status of cannabis, research is rapidly expanding, focusing on the plant's bioactive compounds, pharmacological properties, and therapeutic applications. The dominant subject areas are medicine, pharmacology, toxicology, pharmaceutics, biochemistry, genetics, molecular biology, and neuroscience, covering nearly 76 % of the studied papers. Despite limited initial contributions from African countries like Morocco due to legal restrictions, beneficial cannabis research is gaining interest. Future research should prioritize in-depth exploration of specific compounds, comparative studies of cannabis-based products, and rigorous clinical trials. Fostering international collaborations and bridging the gap between research and policymakers are crucial for harnessing the full potential of cannabis while mitigating potential risks. This study serves as a reference for researchers to identify current orientations, blind areas, and gaps in cannabis research, offering suggestions for future studies.
有益的大麻使用引发了研究人员越来越浓厚的兴趣，导致探索其植物化学和应用的实证研究有所增加。然而，对整体研究方向的理解仍然有限。本研究旨在通过对2012年至2022年发表的7841篇文献进行文献计量分析来弥补这一差距。分析显示年增长率为16.83%，重点集中在医学、药理学、毒理学、药剂学、生物化学、遗传学、分子生物学和神经科学领域。绩效分析突出了来源、国家、机构和作者的指标，而科学图谱则确定了关键词、主题演变以及引用/共同作者模式。值得注意的是,摩洛哥尽管最初的贡献有限，但最近在大麻研究方面呈现出稳定增长，年增长率为14.31%，国际合作率为51.72%。本研究为大麻研究的既定领域和潜在研究方向提供了有价值的见解，为受众的更深入理解铺平了道路。随着大麻法律地位的变化，研究正在迅速扩展，重点关注该植物的生物活性化合物、药理特性和治疗应用。主要主题领域是医学、药理学、毒理学、药剂学、生物化学、遗传学、分子生物学和神经科学，涵盖了近76%的研究论文。尽管由于法律限制，像摩洛哥这样的非洲国家最初的贡献有限，但有益的大麻研究正在受到关注。未来的研究应优先深入探索特定化合物、基于大麻的产品的比较研究以及严格的临床试验。促进国际合作并弥合研究与政策制定者之间的差距对于充分发挥大麻的潜力同时降低潜在风险至关重要。本研究为研究人员识别大麻研究的当前方向、盲区和差距提供了参考，为未来研究提供了建议。
