口服免疫疗法：治疗花生过敏的答案？

Oral immunotherapy: The answer to peanut allergy?

机构信息

Department of Allergy and Clinical Immunology, Food Allergy Center of Excellence., Cleveland Clinic.

Department of Pediatric Allergy and Clinical Immunology, Food Allergy Center of Excellence, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.

出版信息

Cleve Clin J Med. 2021 Feb 1;88(2):104-109. doi: 10.3949/ccjm.88a.20130.

DOI:10.3949/ccjm.88a.20130

PMID:33526464

Abstract

Peanut and tree-nut allergies have increased dramatically in prevalence, especially in children. Historically, children with food allergies have been treated through strict avoidance of the allergen. Recently, an oral preparation of peanut allergen (Palforzia) was approved for immunotherapy (ie, desensitization) in children 4 to 17 years old. This article reviews oral immunotherapy and its role in children with peanut allergies.

摘要

花生和树坚果过敏的患病率显著增加，尤其是在儿童中。从历史上看，有食物过敏的儿童通过严格避免过敏原来进行治疗。最近，一种花生过敏原的口服制剂（Palforzia）被批准用于 4 至 17 岁儿童的免疫疗法（即脱敏）。本文综述了口服免疫疗法及其在花生过敏儿童中的作用。