32 家美国急性护理儿童医院头孢曲松剂量的变异性。
Variability in Ceftriaxone Dosing Across 32 US Acute Care Children's Hospitals.
机构信息
Department of Pediatrics, Washington University in St Louis, St Louis, Missouri, USA.
Department of Pediatrics, Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
出版信息
J Pediatric Infect Dis Soc. 2021 May 28;10(5):677-681. doi: 10.1093/jpids/piab004.
Abstract
Ceftriaxone is one of the most common antibiotics prescribed for hospitalized children in the United States. However, ceftriaxone is not dosed consistently. Sepsis/serious bacterial infection had high dosing variability. Dosing for central nervous system infection was frequently suboptimal. Future efforts should focus on optimizing and standardizing ceftriaxone dosing.
摘要
头孢曲松是美国住院儿童最常用的抗生素之一。然而，头孢曲松的剂量并不一致。脓毒症/严重细菌感染的剂量变异性很高。中枢神经系统感染的剂量常常不够理想。未来的工作应重点优化和规范头孢曲松的剂量。
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