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全球对准比例(GAP)评分预测老年退行性脊柱畸形患者术后机械并发症的有效性。

Validity of the global alignment proportion (GAP) score in predicting mechanical complications after adult spinal deformity surgery in elderly patients.

机构信息

Spine Center and Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.

Seoul National University Bundang Hospital, 166 Gumiro Bundang-gu, Seongnam, 463-707, Republic of Korea.

出版信息

Eur Spine J. 2021 May;30(5):1190-1198. doi: 10.1007/s00586-021-06734-2. Epub 2021 Feb 2.

DOI:10.1007/s00586-021-06734-2
PMID:33528658
Abstract

PURPOSE

This study aimed to validate the usefulness of the global alignment proportion (GAP) score to predict postoperative mechanical failure in the elderly (mean age, 70.5 years) individuals with severe sagittal imbalance.

METHODS

A total of 84 patients were enrolled: mechanical complications (MC), minor mechanical complications (mMC), proximal junctional failure (PJF), and revision surgery occurred in 61% (51/84), 58% (49/84), 44% (37/84), and 13% (11/84) of the patients, respectively. The GAP score was calculated using the X-ray obtained in the early postoperative period. The validity of the GAP score's predictive ability was evaluated by calculating the area under the curve (AUC) of the receiver operating characteristics curve. Univariate logistic regression analysis and Cochran-Armitage test of trend were performed to determine the association between mechanical complications and GAP score.

RESULTS

The discriminatory power of GAP score to predict MC, mMC, and PJF was "moderately accurate," with an AUC of 0.839 (confidence interval [CI] 0.755-0.824, p < 0.001), 0.836 (CI 0.749-0.923, p < 0.001), and 0.702 (CI 0.588-0.851, p < 0.001), respectively. The GAP score showed a statistically significant association with MC, mMC, and PJF in univariate logistic regression analysis and Cochran-Armitage test for trend. However, it was not significantly associated with revision surgery.

CONCLUSION

This study showed promising results regarding the GAP score's predictive power for MC, mMC, and PJF in the elderly population with degenerative kyphoscoliosis. Using the GAP score, we can determine the patient's specific correction goal preoperatively to prevent mechanical failure based on individual patient's characteristics such as pelvic incidence.

摘要

目的

本研究旨在验证全球对准比例(GAP)评分在预测老年(平均年龄 70.5 岁)严重矢状失平衡患者术后机械失败方面的有效性。

方法

共纳入 84 例患者:机械并发症(MC)、轻微机械并发症(mMC)、近端交界失败(PJF)和翻修手术分别发生在 61%(51/84)、58%(49/84)、44%(37/84)和 13%(11/84)的患者中。GAP 评分是通过术后早期获得的 X 射线计算得出的。通过计算受试者工作特征曲线下的面积(AUC)来评估 GAP 评分预测能力的有效性。进行单变量逻辑回归分析和 Cochran-Armitage 趋势检验,以确定机械并发症与 GAP 评分之间的关联。

结果

GAP 评分预测 MC、mMC 和 PJF 的区分能力为“中等准确”,AUC 分别为 0.839(95%CI 0.755-0.824,p<0.001)、0.836(95%CI 0.749-0.923,p<0.001)和 0.702(95%CI 0.588-0.851,p<0.001)。单变量逻辑回归分析和 Cochran-Armitage 趋势检验表明,GAP 评分与 MC、mMC 和 PJF 之间存在统计学显著关联。然而,它与翻修手术无显著关联。

结论

本研究表明,GAP 评分在预测老年退行性脊柱侧凸患者 MC、mMC 和 PJF 方面具有良好的预测能力。使用 GAP 评分,我们可以在术前根据患者的骨盆入射角等个体特征确定患者的具体矫正目标,以预防机械失败。

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Spine Deform. 2019 Mar;7(2):331-337. doi: 10.1016/j.jspd.2018.08.002.
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A Comprehensive Review of Complication Rates After Surgery for Adult Deformity: A Reference for Informed Consent.
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