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在 COVID-19 大流行期间,因饮用受污染的手部消毒剂产品而导致的具有地域差异的致命甲醇中毒病例。

A Geographically Distinct Case of Fatal Methanol Toxicity from Ingestion of a Contaminated Hand Sanitizer Product During the COVID-19 Pandemic.

机构信息

Harvard Medical Toxicology Fellowship, Boston Children's Hospital, Boston, MA, USA.

Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

出版信息

J Med Toxicol. 2021 Apr;17(2):218-221. doi: 10.1007/s13181-021-00824-9. Epub 2021 Feb 2.

DOI:10.1007/s13181-021-00824-9
PMID:33528767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7852476/
Abstract

The COVID-19 pandemic has triggered outbreaks of unanticipated toxicities, including methanol toxicity. Multiple methanol outbreaks have been described, including contaminated hand sanitizer in the southwest USA. In this case, we describe a fatal case of methanol toxicity from hand sanitizer ingestion, geographically separated from the outbreak in the southwest USA and prior to the announcement of nationwide warnings by the Food and Drug Administration (FDA). The product was identified as one later recalled by the FDA for methanol contamination. Additionally, the consumption in this case was related to a desire to conceal alcohol consumption from family members. This case of methanol toxicity should increase awareness of the ease of which contaminated products can be widely distributed and of the use of alternative ethanol-containing products to obscure relapse in alcohol use disorder.

摘要

新冠疫情引发了一系列意想不到的毒性事件,包括甲醇毒性。已经描述了多种甲醇中毒事件,包括美国西南部受污染的洗手液。在本例中,我们描述了一起与美国西南部爆发的甲醇中毒事件分离,且在食品药品监督管理局(FDA)发布全国性警告之前发生的致命性洗手液摄入甲醇中毒的案例。该产品后来被 FDA 确认为因甲醇污染而召回的产品之一。此外,本例中毒是由于试图向家庭成员隐瞒饮酒而导致的。本甲醇中毒病例应提高人们对污染产品广泛传播的认识,以及对使用含替代乙醇的产品来掩盖酒精使用障碍复发的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6736/8017019/957caecb48ab/13181_2021_824_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6736/8017019/957caecb48ab/13181_2021_824_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6736/8017019/957caecb48ab/13181_2021_824_Fig1_HTML.jpg

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本文引用的文献

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A study and evaluation of 97 selected cases seen at otologic clinics in the Wisconsin Hearing Conservation Program.对威斯康星听力保护项目耳科诊所所见的97例选定病例的研究与评估。
Wis Med J. 1953 Feb;52(2):137-9.
在慢性酒精中毒背景下,明显因摄入洗手液导致甲醇中毒而引发的五例死亡病例群。
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A cross-sectional multicenter linkage study of hospital admissions and mortality due to methanol poisoning in Iranian adults during the COVID-19 pandemic.伊朗成年人在 COVID-19 大流行期间因甲醇中毒住院和死亡的横断面多中心关联研究。
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