Allergy Service, Hospital Universitario Río Hortega, Valladolid University, Valladolid, Spain;
Allergy Service, Hospital Universitario Río Hortega, Valladolid University, Valladolid, Spain.
Allergol Immunopathol (Madr). 2021 Jan 2;49(1):113-117. doi: 10.15586/aei.v49i1.40. eCollection 2021.
Spain has been severely affected by the COVID-19 epidemic, with 195,944 persons infected and 20,453 deaths at the time of writing. Older people with respiratory or cardiac conditions are most at risk.
The aim was to compare respiratory symptoms in nursing home residents and patients with uncontrolled asthma, who are considered vulnerable to COVID-19.
We studied 134 nursing home residents and 139 patients with uncontrolled asthma, groups vulnerable to COVID-19. Demographic characteristics, clinical manifestations, outcomes, key laboratory results, and radiological images were collected from medical records. COVID-19 infection was detected by polymerase chain reaction (PCR).
Thirteen (9.3%) patients with uncontrolled asthma, all receiving inhaled corticosteroids were infected by COVID-19. Eighty (60%) nursing home residents were infected; only 28, all of whom had received inhaled corticosteroids, had a good prognosis.
Early treatment with inhaled corticosteroids may be helpful in COVID-19 infection. Persons with an allergy might have some protective mechanisms against coronavirus.
西班牙受到 COVID-19 疫情的严重影响，截至撰写时，已有 195944 人感染，20453 人死亡。有呼吸道或心脏疾病的老年人风险最高。
本研究旨在比较养老院居民和未控制的哮喘患者的呼吸道症状，这些人被认为容易感染 COVID-19。
我们研究了 134 名养老院居民和 139 名未控制的哮喘患者，这些人群易感染 COVID-19。从病历中收集了人口统计学特征、临床表现、结局、关键实验室结果和影像学图像。通过聚合酶链反应（PCR）检测 COVID-19 感染。
13 名（9.3%）接受吸入皮质激素治疗的未控制哮喘患者感染了 COVID-19。80 名（60%）养老院居民感染了 COVID-19；只有 28 人预后良好，他们都接受了吸入皮质激素治疗。
早期使用吸入皮质激素治疗可能有助于 COVID-19 感染。过敏的人可能对冠状病毒有一些保护机制。
