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常规与改良额肌瓣前移术治疗重度先天性上睑下垂的对比评价:一项回顾性队列研究。

Comparative evaluation of conventional and modified frontalis muscle flap advancement techniques in the treatment of severe congenital ptosis: A retrospective cohort study.

机构信息

Tianjin Eye Hospital, Tianjin, China.

Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, China.

出版信息

PLoS One. 2021 Feb 2;16(2):e0246183. doi: 10.1371/journal.pone.0246183. eCollection 2021.

Abstract

PURPOSE

To introduce a modified frontalis muscle (FM) flap for use in FM flap advancement surgery and compare it with the conventional flap for correcting severe congenital ptosis.

METHODS

This retrospective cohort study included 200 patients (278 eyes) with severe congenital ptosis treated with FM flap advancement at Tianjin Eye Hospital from April 2018 to October 2019. The patients were divided into two groups: 100 patients (138 eyes) in the conventional group and 100 patients (140 eyes) in the modified group. The success and complication rates were evaluated.

RESULTS

The final success rate was 77.5% (107/138) in the conventional group and 90.0% (126/140) in the modified group (p = 0.005). Undercorrection was observed in 31 eyes (22.5%) in the conventional group and 14 eyes (10%) in the modified group (p = 0.005). In the conventional group, angular deformity of the upper eyelid was observed in 29 eyes (21.0%), FM paralysis in 11 (8.0%), frontal hypoesthesia in 10 (7.2%), severe hematoma in 12 (8.7%), and exposure keratitis in 8 (5.8%); these complications were not observed in the modified group (p <0.001, p <0.001, p = 0.004, p <0.001, p = 0.011, respectively). There were no cases of overcorrection, entropion or ectropion in either group.

CONCLUSION

Compared with the conventional FM flap, the modified FM flap in this study yielded a higher success rate with a clear field of vision, mild trauma, and few complications. This technique is simple and convenient for correcting severe congenital ptosis.

摘要

目的

介绍一种改良的额肌(FM)皮瓣,用于 FM 皮瓣推进术,并将其与传统皮瓣矫正重度先天性上睑下垂进行比较。

方法

本回顾性队列研究纳入 2018 年 4 月至 2019 年 10 月在天津市眼科医院接受 FM 皮瓣推进术治疗的 200 例(278 只眼)重度先天性上睑下垂患者。将患者分为两组:常规组 100 例(138 只眼),改良组 100 例(140 只眼)。评估手术成功率和并发症发生率。

结果

常规组最终成功率为 77.5%(107/138),改良组为 90.0%(126/140)(p=0.005)。常规组中有 31 只眼(22.5%)出现矫正不足,改良组中有 14 只眼(10%)出现矫正不足(p=0.005)。常规组中有 29 只眼(21.0%)出现上睑角度畸形,11 只眼(8.0%)出现 FM 麻痹,10 只眼(7.2%)出现额部感觉减退,12 只眼(8.7%)出现严重血肿,8 只眼(5.8%)出现暴露性角膜炎;改良组未出现上述并发症(p<0.001,p<0.001,p=0.004,p<0.001,p=0.011)。两组均未出现过矫、内翻或外翻。

结论

与传统 FM 皮瓣相比,本研究中改良的 FM 皮瓣具有更高的成功率,视野清晰,创伤小,并发症少。该技术简单方便,适用于矫正重度先天性上睑下垂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e58f/7853494/da8a0410e70f/pone.0246183.g001.jpg

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