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[胰石蛋白,一种慢性胰腺炎的新标志物]

[Pancreatic stone protein, a new marker for chronic pancreatitis].

作者信息

Montalto G, Carroccio A, Notarbartolo A

机构信息

Università degli Studi di Palermo Cattedra di Patologia Medica.

出版信息

Minerva Med. 1988 Feb;79(2):91-4.

PMID:3352949
Abstract

A CaCO3 precipitation and crystal growth inhibitor has recently been isolated from pancreatic calculi and from pancreatic juice. It is a glycoprotein with a molecular weight of 14,000, whose probable physiological role is the stabilization of exocrine pancreatic secretion which is normally supersaturated with CaCO3. It is hoped to determine a simple, but sensitive assay of this new protein on pancreatic juice and on serum, a decrease in which could be a marker for chronic pancreatitis.

摘要

最近从胰腺结石和胰液中分离出一种碳酸钙沉淀和晶体生长抑制剂。它是一种分子量为14000的糖蛋白,其可能的生理作用是稳定通常与碳酸钙呈过饱和状态的胰腺外分泌。希望能找到一种简单而灵敏的方法来检测胰液和血清中的这种新蛋白质,其含量降低可能是慢性胰腺炎的一个标志物。

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