Wiesenfeld-Hallin Z
Department of Clinical Neurophysiology and Physiology, Karolinska Institute, Huddinge University Hospital, Sweden.
Neurosci Lett. 1988 Feb 3;84(3):261-5. doi: 10.1016/0304-3940(88)90517-4.
The innervation territories of the cutaneous nerves to the hindfoot were examined in the rat. Plasma extravasation of Evans blue to antidromic stimulation of C-fibers in the saphenous, sural, peroneal and tibial nerves was the means to determine the innervation areas. A high degree of bilateral symmetry was found for the territory of each nerve in individual rats. Stimulation of pairs of nerves, one on each side, that innervate neighboring skin regions revealed the existence of overlapping territories for all pairs of nerves. The area of overlap was greatest on the toes and just proximal to the toes on the dorsum of the foot, whereas overlap on the volar aspect of the foot was minimal. The need to consider the existence of overlapping cutaneous innervation in normal animals in studies involving collateral sprouting after nerve injuries is discussed.
在大鼠中检查了后足皮神经的支配区域。通过对隐神经、腓肠神经、腓总神经和胫神经中的C纤维进行逆向刺激，观察伊文思蓝的血浆外渗情况，以此来确定神经支配区域。在个体大鼠中，发现每条神经的支配区域具有高度的双侧对称性。刺激支配相邻皮肤区域的双侧神经对，发现所有神经对均存在重叠支配区域。重叠区域在脚趾处以及足背靠近脚趾的近端最大，而足底的重叠区域最小。文中讨论了在涉及神经损伤后侧支发芽的研究中，需要考虑正常动物中存在重叠皮肤神经支配这一情况。
