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从一个声学窗口定量评估整个右心室:先天性心脏病患者日常实践中的一种有吸引力的方法。

Quantitative assessment of the entire right ventricle from one acoustic window: An attractive approach in patients with congenital heart disease in daily practice.

机构信息

Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Cardiology, Antwerp University Hospital, Antwerp, Belgium; University of Antwerp, Antwerp, Belgium.

Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

出版信息

Int J Cardiol. 2021 May 15;331:75-81. doi: 10.1016/j.ijcard.2021.01.050. Epub 2021 Jan 30.

Abstract

BACKGROUND

Right ventricular (RV) function is recognized as an important prognostic factor in adult congenital heart disease (ACHD). The accuracy of established parameters including tricuspid annular plane systolic excursion (TAPSE), RV fractional area change (RVFAC) and tissue Doppler imaging (TDI S') is limited as only a small RV region is reflected. We previously introduced a novel four-view approach with different RV walls visualized from one apical view using electronic plane rotation, also known as iRotate.

AIM

To evaluate the entire RV function using electronic plane rotation echocardiography within the spectrum of ACHD compared with healthy subjects.

METHODS AND RESULTS

One hundred and forty-two ACHD patients were recruited from the outpatient clinic and 89 healthy subjects. All subjects underwent a transthoracic echocardiogram with evaluation of TAPSE, TDI S' and peak systolic longitudinal RV strain (RV-LS) from all RV walls using the four-view electronic plane rotation model. With exception of TDI S' in inferior coronal view, all parameters were lower in ACHD vs healthy subjects (p < 0.001). Within the ACHD patients, RV strain was lower in anterior (-15.9 ± 4.9) and inferior coronal view (-15.1 ± 4.5) versus lateral (-17.6 ± 5.0) and inferior wall (-17.2 ± 4.7) (p < 0.05). RV-LS values of systemic RV were lower (p < 0.05), but no difference was observed between subpulmonic RV loading conditions.

CONCLUSION

The four-view electronic plane rotation model represents a reproducible, easily applicable and complete RV assessment in daily practice. RV function is significantly decreased in the ACHD group using both regional and global assessment parameters. Complete RV strain analysis reveals regional differences.

摘要

背景

右心室(RV)功能被认为是成人先天性心脏病(ACHD)的重要预后因素。包括三尖瓣环平面收缩期位移(TAPSE)、RV 局部射血分数(RVFAC)和组织多普勒成像(TDI S')在内的已有参数的准确性有限,因为仅反映了一小部分 RV 区域。我们之前介绍了一种新的四视图方法,该方法使用电子平面旋转从一个心尖视图显示不同的 RV 壁,也称为 iRotate。

目的

使用电子平面旋转超声心动图评估 ACHD 患者整个 RV 功能,并与健康受试者进行比较。

方法和结果

从门诊招募了 142 例 ACHD 患者和 89 例健康受试者。所有受试者均接受了经胸超声心动图检查,使用四视图电子平面旋转模型评估所有 RV 壁的 TAPSE、TDI S'和 RV 收缩期纵向应变峰值(RV-LS)。除下冠状面 TDI S'外,ACHD 患者的所有参数均低于健康受试者(p<0.001)。在 ACHD 患者中,前壁(-15.9±4.9)和下冠状面(-15.1±4.5)的 RV 应变低于侧壁(-17.6±5.0)和下壁(-17.2±4.7)(p<0.05)。体循环 RV 的 RV-LS 值较低(p<0.05),但亚肺 RV 负荷条件之间无差异。

结论

四视图电子平面旋转模型代表了一种在日常实践中具有可重复性、易于应用和完整的 RV 评估方法。使用区域和全局评估参数,ACHD 组的 RV 功能明显降低。完整的 RV 应变分析显示出区域差异。

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