Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2G2, Canada.
Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2G2, Canada.
Curr Opin Struct Biol. 2021 Jun;68:149-156. doi: 10.1016/j.sbi.2020.12.011. Epub 2021 Jan 30.
Glycans play important roles in the biology of infectious diseases. Although glycans are expressed on both the pathogens and the host, the functions and dynamics of the host glycome during infection are not well understood. Recent years have witnessed new discoveries on the host glycome respsonse to infection, as well as related mechanisms and their implications. Herein, we present a brief review on the latest findings in this field and put them in the context of host immunity.
糖链在传染病生物学中发挥着重要作用。尽管糖链既存在于病原体上，也存在于宿主上，但宿主糖组在感染过程中的功能和动态仍未被很好地理解。近年来，人们对宿主糖组对感染的反应以及相关机制及其意义有了新的发现。在此，我们对该领域的最新发现进行简要综述，并将其置于宿主免疫的背景下。
